使用臂踝指数评估饮食模式对血管衰老的影响

Effect of Dietary Patterns on Vascular Aging Using the Brachial-Ankle Index.

作者信息

Llamas-Ramos Inés, Llamas-Ramos Rocío, Cortés-Rodríguez María, Rodríguez-Sánchez Emiliano, García-Ortiz Luis, Gómez-Marcos Manuel A, Gómez-Sánchez Marta, Gómez-Sánchez Leticia

机构信息

Faculty of Nursing and Physiotherapy, Universidad de Salamanca, 37007 Salamanca, Spain.

Instituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.

出版信息

Nutrients. 2024 Dec 6;16(23):4229. doi: 10.3390/nu16234229.

DOI:10.3390/nu16234229

PMID:39683622

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11644465/

Abstract

UNLABELLED

The Mediterranean diet (MD) plays an important role in delaying vascular aging. The main objective of this study was to analyze the association between adherence to the MD and vascular aging estimated with brachial-ankle pulse wave velocity (ba-PWV) in a Spanish population sample and the differences by sex.

METHODS

Cross-sectional descriptive study. A total of 3437 subjects from the EVA, MARK and EVIDENT studies participated. The ba-PWV was assessed with the Vasera VS-1500 device. Vascular aging was classified as healthy vascular aging (HVA), normal vascular aging (NVA) and early vascular aging (EVA) and adherence to the MD was assessed with the Mediterranean Diet Adherence Screener questionnaire.

RESULTS

The mean age was 60.15 ± 9.55 (60.09 ± 9.71 in women; 60.20 ± 9.43 in men). Overall, MD adherence was observed in 48.0% of subjects (40% in women; 54% in men). The mean value of ba-PWV was 14.38 ± 2.71 (women 14.24 ± 2.89; men 14.49 ± 2.56). In multinomial logistic regression a positive association was found overall between HVA and NVA (OR = 1.751, 95% CI: 1.411-2.174, < 0.001) and between HVA and EVA (OR = 1.501, 95% CI:1.295-1.740, < 0.001); in women between HVA and NVA (OR = 2. 055, 95% CI:1.456-2.901, < 0.001) and between HVA and EVA (OR = 1.413, 95% CI:1.124-1.776; = 0.003); and in men between HVA and NVA (OR = 1.551, 95% CI: 1.175-2.047, = 0.002) and between HVA and EVA (OR = 1.549, 95% CI: 1.275-1.882; < 0.001).

CONCLUSIONS

The results of this work indicate that greater adherence to the MD is associated with healthier vascular aging.

摘要

未标注

地中海饮食（MD）在延缓血管衰老方面发挥着重要作用。本研究的主要目的是分析西班牙人群样本中遵循地中海饮食与通过臂踝脉搏波速度（ba-PWV）评估的血管衰老之间的关联以及性别差异。

方法

横断面描述性研究。共有来自EVA、MARK和EVIDENT研究的3437名受试者参与。使用Vasera VS - 1500设备评估ba-PWV。血管衰老分为健康血管衰老（HVA）、正常血管衰老（NVA）和早期血管衰老（EVA），并使用地中海饮食依从性筛查问卷评估对地中海饮食的依从性。

结果

平均年龄为60.15±9.55岁（女性为60.09±9.71岁；男性为60.20±9.43岁）。总体而言，48.0%的受试者遵循地中海饮食（女性为40%；男性为54%）。ba-PWV的平均值为14.38±2.71（女性为14.24±2.89；男性为14.49±2.56）。在多项逻辑回归中，总体上发现HVA与NVA之间存在正相关（OR = 1.751，95%CI：1.411 - 2.174，P < 0.001）以及HVA与EVA之间存在正相关（OR = 1.501，95%CI：1.295 - 1.740，P < 0.001）；在女性中，HVA与NVA之间（OR = 2.055，95%CI：1.456 - 2.901，P < 0.001）以及HVA与EVA之间（OR = 1.413，95%CI：1.124 - 1.776；P = 0.003）存在正相关；在男性中，HVA与NVA之间（OR = 1.551，95%CI：1.175 - 2.047，P = 0.002）以及HVA与EVA之间（OR = 1.549，95%CI：1.275 - 1.882；P < 0.001）存在正相关。