Nuclear Medicine Unit, Department of Medical-Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome "Sapienza," Rome, Italy.
Center for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, Baltimore, Maryland.
J Nucl Med. 2023 Nov;64(11):1676-1682. doi: 10.2967/jnumed.123.265906. Epub 2023 Sep 28.
The International Atomic Energy Agency organized a technical meeting at its headquarters in Vienna, Austria, in 2022 that included 17 experts representing 12 countries, whose research spanned the development and use of radiolabeled agents for imaging infection. The meeting focused largely on bacterial pathogens. The group discussed and evaluated the advantages and disadvantages of several radiopharmaceuticals, as well as the science driving various imaging approaches. The main objective was to understand why few infection-targeted radiotracers are used in clinical practice despite the urgent need to better characterize bacterial infections. This article summarizes the resulting consensus, at least among the included scientists and countries, on the current status of radiopharmaceutical development for infection imaging. Also included are opinions and recommendations regarding current research standards in this area. This and future International Atomic Energy Agency-sponsored collaborations will advance the goal of providing the medical community with innovative, practical tools for the specific image-based diagnosis of infection.
国际原子能机构于 2022 年在其位于奥地利维也纳的总部组织了一次技术会议，来自 12 个国家的 17 名专家代表参加了会议，他们的研究涵盖了放射性标记物在感染成像中的开发和应用。会议主要集中在细菌病原体上。该小组讨论并评估了几种放射性药物的优缺点，以及推动各种成像方法的科学原理。主要目标是了解为什么尽管迫切需要更好地描述细菌感染，但在临床实践中很少使用针对感染的放射性示踪剂。本文总结了与会者（至少是与会的科学家和国家）对感染成像放射性药物开发现状的共识，同时还包括了对该领域当前研究标准的意见和建议。未来，国际原子能机构主办的合作将推动为医学界提供创新、实用的感染特定成像诊断工具这一目标的实现。
