Pitt Jordan, Shopper Cody, Dowling Paul, Miller Christopher, Sherman Ashley, Aljubran Salman
Children's Mercy Kansas City, Mo.
University of Missouri Kansas City, Mo.
J Allergy Clin Immunol Glob. 2022 Aug 12;1(4):312-313. doi: 10.1016/j.jacig.2022.05.010. eCollection 2022 Nov.
General recommendations for delaying allergy testing, especially skin testing, in the weeks following anaphylaxis have been proposed owing to concern for false-negative results. However, no specific guidelines exist to aid clinicians in the decision regarding when to perform postanaphylactic food allergy testing and which test to use. The current practices of allergists regarding a delay in testing for food allergy after anaphylaxis are unknown.
We aimed to quantify the use of different approaches to postanaphylactic food allergy testing among allergists across the United States.
A clinical scenario was presented to 82 allergy and immunology fellowship program directors via e-mail survey. They were asked whether they avoid skin prick and/or blood-specific IgE testing in a child in the 6 weeks following suspected food-induced anaphylaxis owing to concern for false-negative results.
The survey response rate was 33%. Of the 27 respondents, 4 (14.8%) avoid both blood and skin testing, 7 (25.9%) avoid skin testing only, and 16 (59.3%) do not avoid any testing.
Given the paucity of published evidence, a spectrum of opinions exists regarding testing in the weeks following food-induced anaphylaxis. About 40% of the allergy and immunology fellowship program directors in the United States who responded to the survey in this study avoid some allergy testing in the first 6 weeks after food-induced anaphylaxis owing to concern for false-negative results.
由于担心出现假阴性结果，已有人提出在过敏反应发生后的数周内推迟过敏测试，尤其是皮肤测试的一般建议。然而，目前尚无具体指南可帮助临床医生决定何时进行过敏反应后的食物过敏测试以及使用何种测试方法。目前过敏症专科医生对于过敏反应后推迟食物过敏测试的实际做法尚不清楚。
我们旨在量化美国各地过敏症专科医生对过敏反应后食物过敏测试的不同方法的使用情况。
通过电子邮件调查向82位过敏与免疫学专科培训项目主任呈现了一个临床病例。询问他们是否因担心假阴性结果而在疑似食物诱发的过敏反应后的6周内避免对儿童进行皮肤点刺和/或血液特异性IgE检测。
调查回复率为33%。在27位受访者中，4人（14.8%）同时避免血液和皮肤检测，7人（25.9%）仅避免皮肤检测，16人（59.3%）不避免任何检测。
鉴于已发表的证据匮乏，对于食物诱发的过敏反应后的检测存在一系列不同观点。在本研究中回复调查的美国过敏与免疫学专科培训项目主任中，约40%的人因担心假阴性结果而在食物诱发的过敏反应后的前6周内避免进行某些过敏检测。
