GenArk：迈向百万个 UCSC 基因组浏览器。
GenArk: towards a million UCSC genome browsers.
机构信息
Genomics Institute, University of California, Santa Cruz, CA, 95064, USA.
LOEWE Centre for Translational Biodiversity Genomics, Senckenberganlage 25, 60325, Frankfurt, Germany.
出版信息
Genome Biol. 2023 Oct 2;24(1):217. doi: 10.1186/s13059-023-03057-x.
Interactive graphical genome browsers are essential tools in genomics, but they do not contain all the recent genome assemblies. We create Genome Archive (GenArk) collection of UCSC Genome Browsers from NCBI assemblies. Built on our established track hub system, this enables fast visualization of annotations. Assemblies come with gene models, repeat masks, BLAT, and in silico PCR. Users can add annotations via track hubs and custom tracks. We can bulk-import third-party resources, demonstrated with TOGA and Ensembl gene models for hundreds of assemblies.Three thousand two hundred sixty-nine GenArk assemblies are listed at https://hgdownload.soe.ucsc.edu/hubs/ and can be searched for on the Genome Browser gateway page.
交互式图形基因组浏览器是基因组学的重要工具，但它们并不包含所有最新的基因组组装。我们从 NCBI 组装中创建了 UCSC 基因组浏览器的 Genome Archive (GenArk) 集合。基于我们成熟的轨迹中心系统，这使得注释的快速可视化成为可能。组装带有基因模型、重复掩蔽、BLAT 和计算机 PCR。用户可以通过轨迹中心和自定义轨迹添加注释。我们可以批量导入第三方资源，通过 TOGA 和 Ensembl 基因模型为数百个组装演示。在 https://hgdownload.soe.ucsc.edu/hubs/ 上列出了 3269 个 GenArk 组装，并且可以在基因组浏览器网关页面上搜索。
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