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对临床引入的用于乳腺癌放射治疗计划的深度学习模型的评估。

Evaluation of a clinically introduced deep learning model for radiotherapy treatment planning of breast cancer.

作者信息

Bakx Nienke, van der Sangen Maurice, Theuws Jacqueline, Bluemink Johanna, Hurkmans Coen

机构信息

Department of Radiation Oncology, Catharina Hospital, Eindhoven, The Netherlands.

Faculties of Applied Physics and Electrical Engineering, Technical University Eindhoven, Eindhoven, The Netherlands.

出版信息

Phys Imaging Radiat Oncol. 2023 Sep 27;28:100496. doi: 10.1016/j.phro.2023.100496. eCollection 2023 Oct.

DOI:10.1016/j.phro.2023.100496
PMID:37789873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10544072/
Abstract

Deep learning (DL) models are increasingly studied to automate the process of radiotherapy treatment planning. This study evaluates the clinical use of such a model for whole breast radiotherapy. Treatment plans were automatically generated, after which planners were allowed to manually adapt them. Plans were evaluated based on clinical goals and DVH parameters. Thirty-seven of 50plans did fulfill all clinical goals without adjustments. Thirteen of these 37 plans were still adjusted but did not improve mean heart or lung dose. These results leave room for improvement of both the DL model as well as education on clinically relevant adjustments.

摘要

深度学习(DL)模型越来越多地被用于自动化放射治疗计划制定过程。本研究评估了此类模型在全乳放疗中的临床应用。自动生成治疗计划后,计划制定者可以手动调整这些计划。根据临床目标和剂量体积直方图(DVH)参数对计划进行评估。50个计划中有37个无需调整即可满足所有临床目标。这37个计划中有13个仍进行了调整,但并未降低心脏或肺部的平均剂量。这些结果为改进DL模型以及临床相关调整的教育留出了空间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/10544072/91a4f2fd2081/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/10544072/91a4f2fd2081/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/10544072/91a4f2fd2081/gr1.jpg

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本文引用的文献

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Knowledge-based automatic plan optimization for left-sided whole breast tomotherapy.基于知识的左侧全乳断层放疗自动计划优化
Phys Imaging Radiat Oncol. 2022 Jun 23;23:54-59. doi: 10.1016/j.phro.2022.06.009. eCollection 2022 Jul.
3
Towards a safe and efficient clinical implementation of machine learning in radiation oncology by exploring model interpretability, explainability and data-model dependency.
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通过探索模型的可解释性、可解释性和数据-模型依赖性,实现机器学习在放射肿瘤学中的安全高效临床应用。
Phys Med Biol. 2022 May 27;67(11). doi: 10.1088/1361-6560/ac678a.
4
Clinical evaluation of two AI models for automated breast cancer plan generation.两种用于自动生成乳腺癌计划的人工智能模型的临床评估。
Radiat Oncol. 2022 Feb 5;17(1):25. doi: 10.1186/s13014-022-01993-9.
5
Sharp loss: a new loss function for radiotherapy dose prediction based on fully convolutional networks.严重亏损:一种基于全卷积网络的新放射治疗剂量预测损失函数。
Biomed Eng Online. 2021 Oct 9;20(1):101. doi: 10.1186/s12938-021-00937-w.
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