He Qiyu, Tan Zhimin, Chen Dongxu, Li Hong, Zhou Liang
Department of Urology, West China Hospital of Sichuan University, Sichuan Province, Chengdu, 610041, China.
Department of Anaesthesiology, West China Hospital of Sichuan University, Sichuan Province, Chengdu, 610041, China.
Lasers Med Sci. 2023 Oct 4;38(1):230. doi: 10.1007/s10103-023-03897-w.
Raman spectroscopy exhibits potential as a tool for identifying the chemical composition of substances and has witnessed a growing application in urological oncology. This study undertook a bibliometric analysis to chart the present state and future prospects of Raman spectroscopy applications in urological tumors. The present study retrieved literature on the utilization of Raman spectroscopy in urological oncology from the Science Citation Index Expanded of Web of Science Core Collection, spanning from its inception to June 2023. Data from included studies were analyzed using CiteSpace, Python, and Excel. Our study examined 897 articles from 65 countries and identified a significant exponential growth in annual publications. The USA and China were prominent contributors to this field, with high publication rates and funding agencies. Shanghai Jiao Tong University emerged as the most influential institution. The journals Analytical Chemistry and Analyst were found to be the most productive. Our keyword analysis revealed an intense interest for "gold nanoparticle" and "pathology," with the most recent bursts occurring for "surface-enhanced Raman scattering (SERS)," "biomarkers," and "prostate specific antigen." As a detection tool, Raman spectroscopy holds the potential to assist in the identification, management, and prognostication of urological tumors. Notably, adjuvant diagnosis and prognosis evaluation based on SERS of tumor markers is a hot research topic. These findings offer valuable insights into the current state of Raman spectroscopy research in urological oncology, which could inform future studies and clinical practice.
拉曼光谱作为一种识别物质化学成分的工具具有潜力，并且在泌尿肿瘤学中的应用日益广泛。本研究进行了文献计量分析，以描绘拉曼光谱在泌尿肿瘤中的应用现状和未来前景。本研究从科学网核心合集的科学引文索引扩展版中检索了关于拉曼光谱在泌尿肿瘤学中应用的文献，时间跨度从其创刊到2023年6月。使用CiteSpace、Python和Excel对纳入研究的数据进行分析。我们的研究审查了来自65个国家的897篇文章，并发现年度出版物呈显著指数增长。美国和中国是该领域的主要贡献者，发表率和资助机构都很高。上海交通大学是最具影响力的机构。发现《分析化学》和《分析家》杂志是最具生产力的。我们的关键词分析显示，人们对“金纳米颗粒”和“病理学”有着浓厚兴趣，最近出现爆发的关键词是“表面增强拉曼散射（SERS）”、“生物标志物”和“前列腺特异性抗原”。作为一种检测工具，拉曼光谱有潜力协助泌尿肿瘤的识别、管理和预后判断。值得注意的是，基于肿瘤标志物SERS的辅助诊断和预后评估是一个热门研究课题。这些发现为泌尿肿瘤学中拉曼光谱研究的现状提供了有价值见解，并可为未来研究和临床实践提供参考。
