François B, Cahen R, Pascal B
Br J Urol. 1986 Oct;58(5):479-83. doi: 10.1111/j.1464-410x.1986.tb05450.x.
The excretion of four inhibitors of urinary stone formation (zinc, magnesium, citrates and glycosaminoglycans (GAG) was studied in 20 normal controls and 40 recurrent calcium stone formers who were placed on a fixed diet restricted in calcium, oxalates and purines. We were unable to show any abnormality in the excretion of Zn, Mg or GAG. In 11 patients, a low level of urinary citrate was a significant feature that was associated in most cases with a urinary pH value above 6. Citrate concentration (per litre) and output (per 24 h) were found to be lower than in the controls in 19 and 33% respectively of the determinations. The overall ratio of average urinary citrate concentration in patients and controls was 0.56, a figure in agreement with previous data.
在20名正常对照者和40名复发性钙结石形成者中研究了四种尿结石形成抑制剂（锌、镁、柠檬酸盐和糖胺聚糖（GAG））的排泄情况，这些患者采用限制钙、草酸盐和嘌呤的固定饮食。我们未能发现锌、镁或GAG排泄有任何异常。在11名患者中，尿柠檬酸盐水平低是一个显著特征，在大多数情况下与尿pH值高于6有关。分别有19%和33%的测定结果显示，患者的柠檬酸盐浓度（每升）和排泄量（每24小时）低于对照组。患者与对照组尿柠檬酸盐平均浓度的总体比值为0.56，这一数字与先前数据一致。
