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自我管理与临床医生管理的堕胎方式与自我报告的堕胎并发症之间的关联:印度的一项横断面分析

The Association Between Self-Managed versus Clinician-Managed Abortion and Self-Reported Abortion Complications: A Cross-Sectional Analysis in India.

作者信息

Goemans Sophie, Singh Abhishek, Yadav Ajit Kumar, McDougal Lotus, Raj Anita, Averbach Sarah H

机构信息

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.

Department of Public Health & Mortality Studies, International Institute for Population Sciences, Mumbai, Maharashtra, India.

出版信息

Int J Womens Health. 2023 Sep 28;15:1467-1473. doi: 10.2147/IJWH.S414599. eCollection 2023.

DOI:10.2147/IJWH.S414599
PMID:37795194
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10545903/
Abstract

PURPOSE

To examine the association between self-managed abortion and the self-reported experience of abortion complications in India, a country with a high incidence of self-managed abortion.

PATIENTS AND METHODS

The study used a cross-sectional multivariable logistic regression analysis of data from the National Family Health Survey (NFHS-4) of 2015-2016 to compare the odds of self-reported complications experienced during abortion between self-managed and clinician-managed abortions in India.

RESULTS

On average, self-managed abortions occurred earlier in gestation than clinician-managed abortions, 7.8 weeks and 11.3 weeks, respectively (p < 0.001). Self-managed abortion was associated with fewer self-reported abortion-related complications than clinician-managed abortions when adjusted for covariates not including gestational age (Adjusted Odds Ratio (aOR) 0.82, 95% confidence interval (CI) 0.69, 0.97). However, once adjusted for gestational age, there was no longer a clinically meaningful or statistically significant difference in the odds of self-reported complications between self-managed and clinician-managed abortions (aOR = 0.98, 95% CI 0.81, 1.18).

CONCLUSION

These findings suggest that people in India are using safe methods to self-manage abortions and support the hypothesis that self-managed abortion can improve access to abortion and reproductive choice without increasing risk.

摘要

目的

在自行管理堕胎发生率较高的印度,研究自行管理堕胎与自我报告的堕胎并发症经历之间的关联。

患者与方法

本研究对2015 - 2016年全国家庭健康调查(NFHS - 4)的数据进行横断面多变量逻辑回归分析,以比较印度自行管理堕胎和临床医生管理堕胎中自我报告的堕胎期间并发症发生几率。

结果

平均而言,自行管理堕胎发生时的孕周比临床医生管理堕胎更早,分别为7.8周和11.3周(p < 0.001)。在不包括孕周的协变量调整后,自行管理堕胎与临床医生管理堕胎相比,自我报告的与堕胎相关的并发症更少(调整优势比(aOR)为0.82,95%置信区间(CI)为0.69,0.97)。然而,一旦调整孕周,自行管理堕胎和临床医生管理堕胎在自我报告并发症几率方面不再存在具有临床意义或统计学意义的差异(aOR = 0.98,95% CI为0.81,1.18)。

结论

这些发现表明,印度民众正在使用安全方法自行管理堕胎,并支持以下假设,即自行管理堕胎可以在不增加风险的情况下改善堕胎可及性和生殖选择。

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本文引用的文献

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Effectiveness of self-managed medication abortion with accompaniment support in Argentina and Nigeria (SAFE): a prospective, observational cohort study and non-inferiority analysis with historical controls.阿根廷和尼日利亚(SAFE)自我管理药物流产伴伴随支持的效果:一项前瞻性、观察性队列研究和与历史对照的非劣效性分析。
Lancet Glob Health. 2022 Jan;10(1):e105-e113. doi: 10.1016/S2214-109X(21)00461-7. Epub 2021 Nov 18.
2
Scoping review of research on self-managed medication abortion in low-income and middle-income countries.低收入和中等收入国家自我管理药物流产研究的范围综述
BMJ Glob Health. 2021 May;6(5). doi: 10.1136/bmjgh-2020-004763.
3
Use of directed acyclic graphs (DAGs) to identify confounders in applied health research: review and recommendations.应用健康研究中使用有向无环图(DAG)识别混杂因素:综述与建议。
Int J Epidemiol. 2021 May 17;50(2):620-632. doi: 10.1093/ije/dyaa213.
4
Self-managed abortion: A systematic scoping review. 自我管理的堕胎:系统范围界定综述。
Best Pract Res Clin Obstet Gynaecol. 2020 Feb;63:87-110. doi: 10.1016/j.bpobgyn.2019.08.002. Epub 2019 Aug 22.
5
Understandings of self-managed abortion as health inequity, harm reduction and social change.将自我管理堕胎理解为健康不平等、减少伤害和社会变革。
Reprod Health Matters. 2018 Nov;26(54):13-19. doi: 10.1080/09688080.2018.1511769. Epub 2018 Sep 19.
6
Gestational dating using last menstrual period and bimanual exam for medication abortion in pharmacies and health centers in Nepal.尼泊尔的药房和卫生中心使用末次月经和双合诊来确定药物流产的孕龄。
Contraception. 2018 Oct;98(4):296-300. doi: 10.1016/j.contraception.2018.06.004. Epub 2018 Jun 21.
7
Medical Abortion Provision by Pharmacies and Drug Sellers in Low- and Middle-Income Countries: A Systematic Review.中低收入国家的药店和药品销售者提供药物流产服务:系统评价。
Stud Fam Plann. 2018 Mar;49(1):57-70. doi: 10.1111/sifp.12049.
8
The incidence of abortion and unintended pregnancy in India, 2015.2015 年印度堕胎和意外妊娠的发生率。
Lancet Glob Health. 2018 Jan;6(1):e111-e120. doi: 10.1016/S2214-109X(17)30453-9.
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Delivering medical abortion at scale: a study of the retail market for medical abortion in Madhya Pradesh, India.大规模提供药物流产服务:印度中央邦药物流产零售市场研究
PLoS One. 2015 Mar 30;10(3):e0120637. doi: 10.1371/journal.pone.0120637. eCollection 2015.
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Use of medicines changing the face of abortion.药物的使用正在改变堕胎的面貌。
Int Perspect Sex Reprod Health. 2012 Sep;38(3):164-6. doi: 10.1363/3816412.