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围产期晚期妊娠的扎拉伊比山羊的血流动力学变化。

Hemodynamic changes in late advanced pregnant Zaraibi goats during the peripartum period.

作者信息

Madbouly Hager, El-Shahat K H, Fathi Mohamed, Abdelnaby Elshymaa A

机构信息

Theriogenology Department, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.

出版信息

BMC Vet Res. 2023 Oct 6;19(1):194. doi: 10.1186/s12917-023-03745-7.

Abstract

The objective of the present study was to demonstrate the blood flow velocities, blood flow rate (BFR; bpm) with the accurate ratio of both systolic and diastolic velocities points (S/D) in addition to Doppler indices (resistive and pulsatility index [RI and PI]) in both fetal [fetal heart (FH), fetal abdominal aorta (Ab. A), and umbilical artery (UM.A)] and maternal [Middle uterine artery (MU.A)] sides during the last month of gestation. Ten Zaraibi (Egyptian Nubian) goats weighing 40-50kg and aged from 5-7 years were examined twice per month till reached the last month of pregnancy. Then all females were examined every 5 days starting from day -35 till day -1 before kidding.The pregnant goats were examined by ultrasonic and Doppler indices were recorded with Doppler scanning (7.5 -12 MHz, with colored and spectral graph to form the perfect wave to assess Doppler measurements). The obtained data were analyzed using analysis of variance. Results indicated that on the fetal side; the maximum point of velocity (MSV; cm/sec) in the FH and BFRwere elevated from day -35 till day -10 with a slight decline at days -5 and -1 at the peripartum period (P < 0.05), while FH.PI and S/D ratio declined till day -1(P < 0.05). In addition, the fetal Ab. A, and UM.A PI, RI, and S/D ratio declined from day -35 till day -1 at the peripartum period with a significant increase in the peak systolic velocity (PSV) and BFR(P < 0.05). However, non-significant changes in the end diastolic velocity (EDV) were detected. On the maternal side, the MU.A PI and S/D declined from day -35 till day -1 with an elevation of both PSV and BFRat the same time points (P < 0.05). In conclusion, the Doppler evaluation of fetal and maternal blood flow vessels is important to give complete information that directly affects the health status of the mother and fetus.

摘要

本研究的目的是在妊娠最后一个月期间,展示胎儿[胎儿心脏(FH)、胎儿腹主动脉(Ab.A)和脐动脉(UM.A)]和母体[子宫中动脉(MU.A)]两侧的血流速度、血流率(BFR;bpm)以及收缩期和舒张期速度点的准确比值(S/D),此外还有多普勒指数(阻力指数和搏动指数[RI和PI])。选取10只体重40 - 50千克、年龄5 - 7岁的扎拉伊比(埃及努比亚)山羊,每月检查两次,直至怀孕最后一个月。然后从产前35天开始,每隔5天对所有母羊进行检查,直至分娩前1天。通过超声检查怀孕山羊,并使用多普勒扫描(7.5 - 12兆赫,彩色和频谱图形成完美波形以评估多普勒测量)记录多普勒指数。使用方差分析对获得的数据进行分析。结果表明,在胎儿一侧,FH中的最大速度点(MSV;厘米/秒)和BFR从产前35天到产前10天升高,在围产期的产前5天和产前1天略有下降(P < 0.05),而FH.PI和S/D比值在产前1天之前下降(P < 0.05)。此外,胎儿Ab.A和UM.A的PI、RI以及S/D比值在围产期从产前35天到产前1天下降,同时收缩期峰值速度(PSV)和BFR显著增加(P < 0.05)。然而,未检测到舒张末期速度(EDV)的显著变化。在母体一侧,MU.A的PI和S/D从产前35天到产前1天下降,同时在相同时间点PSV和BFR升高(P < 0.05)。总之,对胎儿和母体血管的多普勒评估对于提供直接影响母亲和胎儿健康状况的完整信息很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5df1/10559465/fa61acd7fff9/12917_2023_3745_Fig1_HTML.jpg

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