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胰岛素依赖型糖尿病儿童的甲状腺功能

Thyroid function in insulin-dependent diabetic children.

作者信息

Słuszkiewicz E

出版信息

Exp Clin Endocrinol. 1986 Aug;87(3):345-8. doi: 10.1055/s-0029-1210566.

DOI:10.1055/s-0029-1210566
PMID:3780868
Abstract

Serum concentrations of thyroxine (T4),3,5,3'-triiodothyronine (T3),3,3',5'-reverse triiodothyronine (rT3),T3-binding capacity (TBC) and TSH were measured in 10 children with diabetes mellitus (mean age: 12.8 +/- 2 yr). The children were without ketoacidosis and serum glucose concentrations were 10.64 +/- 1.68 mmol/l (SD). The mean concentrations of serum T4, T3, rT3, TBC and TSH were 116.35 +/- 10.68 nmol/l (SD), 2.81 +/- 0.33 nmol/l, 0.27 +/- 0.04 nmol/l, 1.087 +/- 0.031 and 3.16 +/- 0.9 mu IU/ml, respectively, which were not significantly different from values of 10 normal control subjects (mean age: 11.6 +/- 2 yr). It seems therefore that the thyroid hormones and TSH levels between well controlled diabetic and healthy subjects of pediatric age do not differ significantly.

摘要

对10名糖尿病患儿(平均年龄:12.8±2岁)测定了血清甲状腺素(T4)、3,5,3'-三碘甲状腺原氨酸(T3)、3,3',5'-反三碘甲状腺原氨酸(rT3)、T3结合能力(TBC)和促甲状腺激素(TSH)的浓度。这些患儿无酮症酸中毒,血清葡萄糖浓度为10.64±1.68 mmol/l(标准差)。血清T4、T3、rT3、TBC和TSH的平均浓度分别为116.35±10.68 nmol/l(标准差)、2.81±0.33 nmol/l、0.27±0.04 nmol/l、1.087±0.031和3.16±0.9 μIU/ml,与10名正常对照受试者(平均年龄:11.6±2岁)的值无显著差异。因此,在儿科年龄组中,血糖控制良好的糖尿病患者与健康受试者之间的甲状腺激素和TSH水平似乎无显著差异。

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