Gulrandhe Purva, Acharya Sourya, Shukla Samarth, Patel Maharshi
Department of Physiotherapy, Ravi Nair Physiotherapy College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2023 Sep 7;15(9):e44819. doi: 10.7759/cureus.44819. eCollection 2023 Sep.
Neurological disease is on the upswing, the second leading cause of mortality and a significant cause of disability. The term emphasizes a dynamic two-way communication between the central nervous system and the gastrointestinal system. The microbiome is being linked to more and more clinical and preclinical studies as a major risk factor for neurological diseases. Overall, 288 studies were identified initially. After screening, data extraction, and applying the inclusion and exclusion criteria, 37 articles were included in the study. Changes in the gut microbial population composition have been correlated to many neurological and neurodevelopmental diseases.
神经系统疾病呈上升趋势，是第二大致死原因和导致残疾的重要原因。这个术语强调中枢神经系统和胃肠系统之间动态的双向交流。微生物群作为神经系统疾病的主要风险因素，正与越来越多的临床和临床前研究联系起来。总体而言，最初识别出288项研究。经过筛选、数据提取并应用纳入和排除标准后，37篇文章被纳入该研究。肠道微生物种群组成的变化已与许多神经和神经发育疾病相关联。
