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角膜塑形镜佩戴者的二维周边屈光和视网膜图像质量

Two-dimensional peripheral refraction and retinal image quality in orthokeratology lens wearers.

作者信息

Lin Zhenghua, Duarte-Toledo Raul, Manzanera Silvestre, Lan Weizhong, Artal Pablo, Yang Zhikuan

机构信息

Aier School of Ophthalmology, Central South University, Changsha, China.

Laboratorio de Óptica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain.

出版信息

Biomed Opt Express. 2020 Jun 4;11(7):3523-3533. doi: 10.1364/BOE.397077. eCollection 2020 Jul 1.

Abstract

Orthokeratology (O-K) is a common procedure that uses rigid contact lenses to reshape the cornea while worn overnight. Beyond the correction of refractive error, it has been suggested that this approach can also be used to reduce myopia progression, possibly because it induces changes in peripheral optics. As this hypothesis remains unproven, the aim of the present study was to explore changes in peripheral retinal optical quality in a group of myopic children following O-K treatment. We provide a comprehensive description of optical characteristics in a group of myopes before and after achieving stable corneal reshaping using overnight O-K lenses. These characteristics extended across the central visual field (60° horizontal x 36° vertical) as measured with a custom Hartmman-Shack wavefront sensor. After corneal reshaping, peripheral refraction was found to be asymmetrically distributed, with a myopic relative refraction of approximately 3D in the temporal retina. Astigmatism and higher order aberrations also increased in the temporal side. Based on corneal topography following treatment, subjects were divided into two groups: Centred Treatment (CT, decentration ∈ [-0.5 + 0.5] mm) and Slightly Decentred Treatment (subjects with more decentred lenses). The process was also modelled by ray-tracing simulation. The results indicate that increased myopia in the temporal retina is caused by the decentration of lenses towards the temporal side. Peripheral optics differ significantly following O-K lens treatment, but further research is required to determine whether this is likely to affect myopia progression.

摘要

角膜塑形术(O-K)是一种常见的治疗方法,它使用硬性隐形眼镜在夜间佩戴时重塑角膜。除了矫正屈光不正外,有人认为这种方法还可用于减缓近视进展,这可能是因为它会引起周边光学变化。由于这一假设尚未得到证实,本研究的目的是探讨一组近视儿童在接受角膜塑形术治疗后周边视网膜光学质量的变化。我们全面描述了一组近视患者在使用夜间角膜塑形镜实现稳定角膜重塑前后的光学特征。这些特征通过定制的哈特曼-夏克波前传感器测量,覆盖了中央视野(水平60°×垂直36°)。角膜重塑后,发现周边屈光度呈不对称分布,颞侧视网膜的近视相对屈光度约为3D。颞侧的散光和高阶像差也有所增加。根据治疗后的角膜地形图,将受试者分为两组:中心治疗组(CT,偏心度∈[-0.5 + 0.5]mm)和轻度偏心治疗组(镜片偏心度更大的受试者)。该过程也通过光线追踪模拟进行了建模。结果表明,颞侧视网膜近视增加是由镜片向颞侧偏心所致。角膜塑形镜治疗后周边光学特性有显著差异,但还需要进一步研究以确定这是否可能影响近视进展。

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