Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, Indonesia.
Natural Products Research Group, Organic Chemistry Division, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Bandung, Indonesia.
Nat Prod Res. 2024 Nov;38(22):3950-3956. doi: 10.1080/14786419.2023.2269596. Epub 2023 Oct 14.
A new lactone, collectindolide (), as well as three known compounds, ()-sydonic acid (), ()-hidroxysydonic acid (), and indole-3-aceticacid () were obtained from the liquid media of , which was obtained from . The chemical structures of were established by spectroscopic analyses, including NMR experiments and by HR-ESI-TOF-MS mass spectroscopy. Compounds - were evaluated for their cytotoxicity against murine leukaemia P-388 cell lines by MTT assay. Antibacterial activity of compounds - was also assayed against four bacteria. Phytochemical investigation of the genus derived from the plant genus is reported for the first time.
从植物内生真菌 中分离得到的液体培养基中得到了一个新的内酯化合物 collectindolide (),以及三个已知化合物:()-sydonic 酸 ()、()-hidroxysydonic 酸 ()和吲哚-3-乙酸 ()。化合物的化学结构通过包括 NMR 实验和 HR-ESI-TOF-MS 质谱在内的光谱分析确定。通过 MTT 测定法评估了化合物 - 对 P-388 白血病细胞系的细胞毒性。还对化合物 - 的抗菌活性进行了四种细菌的检测。这是首次对来源于植物属 的属内生真菌进行的植物化学研究。