Institute for Global Rare Disease Network, Professional Graduate School of Korean Medicine, Wonkwang University, Iksan, Republic of Korea.
Adv Exp Med Biol. 2023;1438:107-112. doi: 10.1007/978-3-031-42003-0_18.
Over the past 5000 years, acupuncture has been practiced in Korea, China, and Japan to relieve various diseases, and it is now widely used and accepted worldwide. Although the anatomical substance and function of meridians has been actively studied, it is still not clearly defined. One of the keys to acupuncture is determining the specific anatomical location exactly on or under the skin. We discovered that the skin primo node is a new anatomical structure in the skin of rats. The present study aimed to analyze the relationship between skin primo nodes and acupoints through changes in the expression of tissue concentrations of skin primo nodes. Analysis of this skin primo node confirmed that the skin primo node after acupuncture had a significantly higher concentration of sulfur and calcium than found in normal skin. And the significant pO in the skin primo node was confirmed by measuring pO using a needle oxygen sensor. Through sulfur, calcium, and pO concentration values of skin primo nodes, we confirmed whether these nodes could be related to acupoint. To understand the clear structure and function of this node, it is necessary to further study through the known properties of acupoints and the function of Primo Vascular System (PVS).
在过去的 5000 年中，针灸已在韩国、中国和日本得到实践，以缓解各种疾病，并且现在已在全球范围内得到广泛应用和认可。尽管经络的解剖物质和功能一直受到积极研究，但仍未得到明确界定。针灸的关键之一是准确确定皮肤表面或下方的特定解剖位置。我们发现皮肤原基节点是大鼠皮肤中的一种新的解剖结构。本研究旨在通过分析皮肤原基节点组织浓度的变化来分析皮肤原基节点与穴位之间的关系。对这种皮肤原基节点的分析证实，与正常皮肤相比，针灸后的皮肤原基节点的硫和钙浓度明显更高。通过使用针状氧传感器测量 pO，证实了皮肤原基节点中的显著 pO。通过皮肤原基节点的硫、钙和 pO 浓度值，我们证实了这些节点是否与穴位有关。为了了解该节点的清晰结构和功能，有必要通过已知的穴位特性和 Primo 血管系统 (PVS) 的功能进一步研究。
