Krishnamoorthy Srikumar, Schwartz Michael F, Van den Broeck Lisa, Hunt Aitch, Horn Timothy J, Sozzani Rosangela
Plant and Microbial Biology Department, North Carolina State University, Raleigh, NC 27695, USA.
Mechanical and Aerospace Engineering Department, North Carolina State University, Raleigh, NC 27695, USA.
Biodes Res. 2021 Dec 2;2021:9890319. doi: 10.34133/2021/9890319. eCollection 2021.
Hydrogel encapsulation has been widely utilized in the study of fundamental cellular mechanisms and has been shown to provide a better representation of the complex microenvironment in natural biological conditions of mammalian cells. In this review, we provide a background into the adoption of hydrogel encapsulation methods in the study of mammalian cells, highlight some key findings that may aid with the adoption of similar methods for the study of plant cells, including the potential challenges and considerations, and discuss key findings of studies that have utilized these methods in plant sciences.
水凝胶包封已广泛应用于基础细胞机制的研究，并已证明能更好地模拟哺乳动物细胞自然生物学条件下的复杂微环境。在本综述中，我们介绍了水凝胶包封方法在哺乳动物细胞研究中的应用背景，强调了一些可能有助于采用类似方法研究植物细胞的关键发现，包括潜在挑战和注意事项，并讨论了在植物科学中使用这些方法的研究的关键发现。
