Carl G F, Keen C L, Gallagher B B, Clegg M S, Littleton W H, Flannery D B, Hurley L S
Neurology. 1986 Dec;36(12):1584-7. doi: 10.1212/wnl.36.12.1584.
A comparison of hospitalized epileptic patients with matched normals showed that the mean whole blood manganese (Mn) concentration of the epileptic population was significantly lower than the mean of the normal population. The whole blood Mn concentration in the epileptics did not correlate either with seizure frequency or with anticonvulsant therapy. It was observed, however, that patients whose epilepsy was a result of trauma had significantly higher blood Mn concentrations than patients whose history was negative for trauma.
对住院癫痫患者与匹配的正常人群进行比较发现，癫痫患者群体的全血锰（Mn）平均浓度显著低于正常人群的平均值。癫痫患者的全血锰浓度与癫痫发作频率或抗惊厥治疗均无关联。然而，观察到因创伤导致癫痫的患者，其血锰浓度显著高于无创伤病史的患者。
