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药物再利用:创新、科学和潜力的交汇点。

Drug repurposing: a nexus of innovation, science, and potential.

机构信息

Institute of Chemical Sciences and Technologies "Giulio Natta" (SCITEC) - CNR, L.go F. Vito 1, 00168, Rome, Italy.

Structural Bioinformatics Lab, CSIR-Institute of Himalayan Bioresource Technology (CSIR-IHBT), Palampur, HP, 176061, India.

出版信息

Sci Rep. 2023 Oct 19;13(1):17887. doi: 10.1038/s41598-023-44264-7.

Abstract

The urgency of finding therapeutic solutions for emerging and existing health challenges has never been more pronounced. In the pursuit of this goal, the value of a strategy that makes use of existing resources is being recognized: drug repurposing or repositioning of compounds for new indications. Such approaches are employed against cancer, rheumatoid arthritis, multiple sclerosis, HIV/AIDS, and many other diseases. This Collection, aptly titled “Drug Repurposing”, includes research and perspectives from scientists at the forefront of this innovative field.

摘要

对于新发和现有健康挑战的治疗方法的需求从未如此迫切。在追求这一目标的过程中,人们越来越认识到利用现有资源的策略的价值:重新利用或重新定位化合物以用于新的适应症。这种方法被用于治疗癌症、类风湿性关节炎、多发性硬化症、艾滋病等许多疾病。本合集恰当地题为“药物再利用”,其中包含处于这一创新领域前沿的科学家们的研究和观点。

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