Institute of Microbiology, University of Veterinary and Animal Sciences, 54000, Lahore, Pakistan.
Institute of Microbiology, University of Veterinary and Animal Sciences, 54000, Lahore, Pakistan.
Microb Pathog. 2023 Dec;185:106401. doi: 10.1016/j.micpath.2023.106401. Epub 2023 Oct 18.
In this study, we checked the effectiveness of L. fermentum IKP 111 in treating S. enteritidis infection in an in vivo study. Its oral administration to broiler chicks significantly reduced the colonization of S. enteritidis in the gut and there was a lower bacterial count of S. enteritidis in the droppings after infection. The administration of the probiotic L. fermentum IKP 111 also led to increase in weight gain in the broiler chicks as well as their immunomodulation against avian influenza virus (AIV) and Newcastle disease virus (NDV) as compared to the chicks challenged only with S. enteritidis. Our study provides evidence that the probiotic strain L. fermentum IKP 111 could be an alternate for controlling S. enteritidis infection while enhancing the gut health as well as the immune response of broiler chickens against viral infections.
在这项研究中，我们通过体内研究来检验 L. fermentum IKP 111 治疗 S. enteritidis 感染的效果。结果表明，该益生菌通过口服处理肉鸡雏鸡，可以显著减少 S. enteritidis 在肠道中的定植，且在感染后粪便中的 S. enteritidis 细菌计数也更低。与仅用 S. enteritidis 攻毒的雏鸡相比，益生菌 L. fermentum IKP 111 的使用还可以提高肉鸡雏鸡的体重增加，并对其产生免疫调节作用，以对抗禽流感病毒（AIV）和新城疫病毒（NDV）。我们的研究结果表明，益生菌菌株 L. fermentum IKP 111 可以替代控制 S. enteritidis 感染，同时增强肉鸡的肠道健康和对病毒感染的免疫反应。
