Perlmutt L M, Braun S D, Newman G E, Oke E J, Dunnick N R
Radiology. 1987 Jan;162(1 Pt 1):187-9. doi: 10.1148/radiology.162.1.3786760.
Pulmonary arteriography is an invasive but relatively safe diagnostic procedure. It is generally believed that the presence of pulmonary hypertension is one risk factor that increases the likelihood of a major complication. To assess the magnitude of risk, the reports on 1,434 patients who underwent pulmonary arteriography were retrospectively reviewed, and the occurrence of complications in the 388 (27%) patients with pulmonary hypertension was noted. Major complications related to contrast material injection (excluding allergic reactions) occurred in 30 (2%) of the 1,434 examinations and included two deaths from acute cor pulmonale. Six complications occurred in the 388 patients with pulmonary hypertension and/or elevated right ventricular end-diastolic pressure (RVEDP). The two deaths occurred in patients with severe pulmonary hypertension and elevated RVEDP. Most patients with severe cardiopulmonary compromise tolerated angiography well. The increased risk of studying this group of patients is modest and must be weighed against the potential therapeutic benefits to the patient.
肺动脉造影是一种有创但相对安全的诊断方法。一般认为，肺动脉高压的存在是增加严重并发症可能性的一个危险因素。为评估风险程度，我们回顾性分析了1434例行肺动脉造影患者的报告，并记录了388例（27%）肺动脉高压患者的并发症发生情况。1434例检查中有30例（2%）发生了与造影剂注射相关的严重并发症（不包括过敏反应），其中包括2例因急性肺心病死亡。388例肺动脉高压和/或右心室舒张末期压力（RVEDP）升高的患者发生了6例并发症。2例死亡患者均有严重肺动脉高压和RVEDP升高。大多数严重心肺功能不全的患者对血管造影耐受性良好。研究这组患者增加的风险较小，必须与对患者潜在的治疗益处相权衡。
