Almomani Ensaf Y, Hajjo Rima, Qablan Ahmad, Sabbah Dima A, Al-Momany Abass
Department of Basic Medical Sciences, Faculty of Medicine, Al-Balqa Applied University, Al-Salt, Jordan.
Applied Science Research Center, Applied Science Private University, Amman, Jordan.
Front Med (Lausanne). 2023 Oct 6;10:1211283. doi: 10.3389/fmed.2023.1211283. eCollection 2023.
COVID-19 vaccines continue to save people's lives around the world; however, some vaccine adverse events have been a major concern which slowed down vaccination campaigns. Anecdotal evidence pointed to the vaccine effect on menstruation but evidence from the adverse event reporting systems and the biomedical literature was lacking. This study aimed to investigate the physiological changes in women during menstruation amid the COVID-19 vaccination.
A cross-sectional online survey was distributed to COVID-19 vaccinated women from Nov 2021 to Jan 2022. The results were analyzed using the SPSS software.
Among the 564 vaccinated women, 52% experienced significant menstrual irregularities post-vaccination compared to before regardless of the vaccine type. The kind of menstrual irregularity varied among the vaccinated women, for example, 33% had earlier menstruation, while 35% reported delayed menstruation. About 31% experienced heavier menstruation, whereas 24% had lighter menstrual flow. About 29% had menstruation last longer, but 13% had it shorter than usual. Noteworthy, the menstrual irregularities were more frequent after the second vaccine shot, and they disappeared within 3 months on average. Interestingly, 24% of the vaccinated women reported these irregularities to their gynecologist.
The COVID-19 vaccine may cause physiological disturbances during menstruation. Luckily, these irregularities were short-termed and should not be a reason for vaccine hesitancy in women. Further studies are encouraged to unravel the COVID-19 vaccine adverse effect on women's health.
新冠病毒疾病（COVID-19）疫苗持续在全球拯救人们的生命；然而，一些疫苗不良事件一直是主要关注点，减缓了疫苗接种运动。轶事证据指向疫苗对月经的影响，但缺乏来自不良事件报告系统和生物医学文献的证据。本研究旨在调查新冠病毒疾病疫苗接种期间女性月经期间的生理变化。
2021年11月至2022年1月，对接种新冠病毒疾病疫苗的女性进行了一项横断面在线调查。使用SPSS软件分析结果。
在564名接种疫苗的女性中，52%的人接种疫苗后月经出现了与之前相比显著的不规律，无论疫苗类型如何。接种疫苗的女性月经不规律的类型各不相同，例如，33%的人月经提前，而35%的人报告月经推迟。约31%的人月经量增多，而24%的人月经量减少。约29%的人经期延长，但13%的人经期比平时短。值得注意的是，第二次接种疫苗后月经不规律更为频繁，平均在3个月内消失。有趣的是，24%的接种疫苗的女性向她们的妇科医生报告了这些不规律情况。
新冠病毒疾病疫苗可能会在月经期间引起生理紊乱。幸运的是，这些不规律情况是短期的，不应成为女性对疫苗犹豫的原因。鼓励进一步研究以阐明新冠病毒疾病疫苗对女性健康的不良影响。
