Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03082, South Korea.
Department of Biomedical Informatics, CHA University School of Medicine, CHA University, Seongnam, 13488, South Korea.
Eur J Med Res. 2023 Oct 24;28(1):455. doi: 10.1186/s40001-023-01426-7.
Rapid decline in balance is a hallmark of aging, elevating the risk of falls and other age-related geriatric illnesses among older adults.
Our aim was to assess whether impairment in balance function is associated with the risk of incident CVD in older adults.
Retrospective cohort analysis.
A total of 129,024 participants who had undergone health screening between 2002 and 2009 were derived from the National Health Insurance Service-Senior cohort.
Balance impairment was evaluated using the open-eyes one-leg standing (OLS) test. The association between balance impairment and incident CVD was analyzed using the Cox proportional hazards regression model. All participants were followed up with until either the date of the first incident of CVD, death, or 31 December 2019.
Those with abnormal balance function (< 10 s in OLS test) had a higher risk of CVD (adjusted hazard ratio [aHR] 1.23, CI 1.16-1.31). The association was significant in both the obese and the non-obese, but it seemed to be more pronounced in the latter. Results were supported by sensitivity analyses that did not include cases of CVD development in the first 1, 2, or 3 years and that used a different criterion to define balance dysfunction (< 9 s in OLS test).
Older adults with balance impairment were found to have an increased risk of incident CVD. Patients with impaired balance function may be a high-risk population who require preventive managements against CVD.
平衡能力迅速下降是衰老的标志，会增加老年人跌倒和其他与年龄相关的老年疾病的风险。
我们旨在评估平衡功能障碍是否与老年人发生心血管疾病（CVD）的风险相关。
回顾性队列分析。
共有 129024 名参与者，他们在 2002 年至 2009 年间接受了健康筛查，这些参与者来自国家健康保险服务-老年队列。
使用睁眼单腿站立（OLS）测试评估平衡障碍。使用 Cox 比例风险回归模型分析平衡障碍与新发 CVD 的关系。所有参与者都随访至首次发生 CVD、死亡或 2019 年 12 月 31 日。
平衡功能异常（OLS 测试<10 秒）的人患 CVD 的风险更高（调整后的危险比[aHR]1.23，CI 1.16-1.31）。在肥胖和非肥胖人群中均存在显著相关性，但在后者中似乎更为明显。敏感性分析结果支持了这一结论，这些分析排除了 CVD 在第 1、2 或 3 年内发展的病例，并且使用不同的标准来定义平衡功能障碍（OLS 测试<9 秒）。
患有平衡障碍的老年人被发现发生新发 CVD 的风险增加。平衡功能受损的患者可能是需要进行 CVD 预防管理的高危人群。
