Alnefaie Sahar M, Alosaimi Mohammed A, Althobaiti Meshal F, Altowairqi Abdulmajeed A, Alrawqi Mohammed K, Alzahrani Sami M, Alnefaie Ghaliah O, Aljaid Maryam S
Department of Surgery, College of Medicine, Taif University, Taif, SAU.
College of Medicine, Taif University, Taif, SAU.
Cureus. 2023 Sep 22;15(9):e45799. doi: 10.7759/cureus.45799. eCollection 2023 Sep.
Introduction Cancer is a condition where abnormal cells proliferate uncontrollably, leading to metastasis, which can be related to death. Breast cancer is the most prevalent type among women worldwide. Early detection with screening mammography has contributed to the decline in breast cancer incidence and mortality. Breast cancer patients are more likely to develop cardiovascular disease, with elderly patients dying from complications. Understanding the patients' cardiovascular status prior to treatment is essential. The study's objective was to evaluate the cardiovascular characteristics of women with breast cancer at diagnosis within the designated time frame of one year. Methodology This was a retrospective study that focused on patients in Taif City, Saudi Arabia, who were initially diagnosed with primary breast cancer over a span of one year. The inclusion criteria encompassed eligible patients, while those not meeting the criteria were excluded. Data extraction from patients' records was conducted, and the analysis was executed using IBM SPSS Statistics for Windows, Version 26.0 (Released 2019; IBM Corp., Armonk, New York, United States). Results This study analyzed the cardiovascular attributes of breast cancer patients, focusing on 136 female cases. The study found significant patterns concerning cardiovascular risk factors in breast cancer patients, categorized by menopausal status. Premenopausal female cases had a mean age of 43.09 ± 8.31 years, while postmenopausal patients had an average age of 58.07 ± 11.70 years. Postmenopausal patients had a higher prevalence of overweight/obesity, irregular menstrual cycles, type II diabetes, hypertension, and hyperlipidemia compared to their premenopausal counterparts. No significant differences were found between the two groups regarding low-density lipoprotein (LDL) cholesterol levels, axillary lymph node metastasis, or distant metastasis. This study emphasized the importance of regular check-ups for menopausal women to detect potential health complications early. Conclusion In summary, breast cancer is a global health concern, and understanding its impact on the cardiovascular system is crucial for comprehensive patient care. A study in Saudi Arabia found associations between cardiovascular risk factors and menopausal status in breast cancer patients. Postmenopausal patients had more prevalent risk factors, emphasizing the need for proactive assessment and management. Age-appropriate screenings and interventions are essential. Integrated healthcare approaches should consider the interplay between breast cancer and cardiovascular health, with medical professionals vigilant in evaluating and addressing risk factors to mitigate complications and optimize long-term outcomes.
引言
癌症是一种异常细胞不受控制地增殖,导致转移,进而可能导致死亡的病症。乳腺癌是全球女性中最常见的类型。通过乳腺钼靶筛查进行早期检测有助于降低乳腺癌的发病率和死亡率。乳腺癌患者更易患心血管疾病,老年患者常死于并发症。在治疗前了解患者的心血管状况至关重要。本研究的目的是在一年的指定时间范围内评估乳腺癌女性患者在诊断时的心血管特征。
方法
这是一项回顾性研究,聚焦于沙特阿拉伯塔伊夫市在一年内首次被诊断为原发性乳腺癌的患者。纳入标准包括符合条件的患者,不符合标准的患者被排除。从患者记录中提取数据,并使用IBM SPSS Statistics for Windows 26.0版(2019年发布;IBM公司,美国纽约州阿蒙克)进行分析。
结果
本研究分析了乳腺癌患者的心血管属性,重点关注136例女性病例。该研究发现了按绝经状态分类的乳腺癌患者心血管危险因素的显著模式。绝经前女性病例的平均年龄为43.09±8.31岁,而绝经后患者的平均年龄为58.07±11.70岁。与绝经前患者相比,绝经后患者超重/肥胖、月经周期不规律、II型糖尿病、高血压和高脂血症的患病率更高。两组在低密度脂蛋白(LDL)胆固醇水平、腋窝淋巴结转移或远处转移方面未发现显著差异。本研究强调了绝经后女性定期检查以早期发现潜在健康并发症的重要性。
结论
总之,乳腺癌是一个全球健康问题,了解其对心血管系统的影响对于全面的患者护理至关重要。沙特阿拉伯的一项研究发现乳腺癌患者的心血管危险因素与绝经状态之间存在关联。绝经后患者的危险因素更为普遍,强调了积极评估和管理的必要性。适合年龄的筛查和干预措施至关重要。综合医疗保健方法应考虑乳腺癌与心血管健康之间的相互作用,医疗专业人员应警惕评估和解决危险因素,以减轻并发症并优化长期结果。