海洋来源青霉属真菌中的抗菌化合物的最新研究进展。

Recent Updates on the Antimicrobial Compounds from Marine-Derived Penicillium fungi.

机构信息

Key Laboratory of Geriatric Nutrition and Health, Ministry of Education of China, School of Light Industry, Beijing Technology and Business University, 100048, Beijing, P. R. China.

School of Ocean Sciences, China University of Geosciences, 100083, Beijing, P. R. China.

出版信息

Chem Biodivers. 2023 Dec;20(12):e202301278. doi: 10.1002/cbdv.202301278. Epub 2023 Nov 14.

DOI:10.1002/cbdv.202301278

PMID:37877324

Abstract

In this review, 72 compounds isolated from marine-derived Penicillium fungi and their antimicrobial activities are reviewed from 2020 to 2023. According to their structures, these compounds can be divided into terpenoids, polyketides, alkaloids and other structural compounds, among which terpenoids and polyketides are relatively large in number. Some compounds have powerful inhibitory effects against different pathogenic bacteria and fungi. This review aims to provide more useful information and enlightenment for further efficient utilization of Penicillium spp. and their secondary metabolites.

摘要

本综述从 2020 年至 2023 年，对 72 种从海洋来源的青霉属真菌中分离得到的化合物及其抗菌活性进行了综述。根据其结构，这些化合物可分为萜类、聚酮类、生物碱和其他结构化合物，其中萜类和聚酮类数量相对较多。一些化合物对不同的病原菌和真菌具有强大的抑制作用。本综述旨在为进一步有效利用青霉属及其次生代谢产物提供更多有价值的信息和启示。