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增强自然力量:唇形科精油与纳米技术在体外和体内医学研究中的应用。

Enhanced Natural Strength: Lamiaceae Essential Oils and Nanotechnology in In Vitro and In Vivo Medical Research.

机构信息

Department of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland.

Department of Economic and Medical Informatics, University of Lodz, 90-214 Lodz, Poland.

出版信息

Int J Mol Sci. 2023 Oct 17;24(20):15279. doi: 10.3390/ijms242015279.

Abstract

The Lamiaceae is one of the most important families in the production of essential oils known to have a wide spectrum of biological activity. Recent research has highlighted the dermatological capabilities of various Lamiaceae essential oils, which appear to offer potential in free radical scavenging and anti-inflammatory activity. Some have also been extensively studied for their tissue remodeling and wound-healing, anti-aging, anti-melanogenic, and anti-cancer properties. Certain Lamiaceae essential oils are promising as novel therapeutic alternatives for skin disorders. This potential has seen substantial efforts dedicated to the development of modern formulations based on nanotechnology, enabling the topical application of various Lamiaceae essential oils. This review provides a comprehensive summary of the utilization of various essential oils from the Lamiaceae family over the past decade. It offers an overview of the current state of knowledge concerning the use of these oils as antioxidants, anti-inflammatory agents, wound-healers, anti-aging agents, anti-melanogenic agents, and anticancer agents, both alone and in combination with nanoparticles. Additionally, the review explores their potential applicability in patents regarding skin diseases.

摘要

唇形科是生产精油的最重要科之一,具有广泛的生物活性。最近的研究强调了各种唇形科精油的皮肤科能力,它们似乎在自由基清除和抗炎活性方面具有潜力。一些精油也因其组织重塑和伤口愈合、抗老化、抗黑色素生成和抗癌特性而被广泛研究。某些唇形科精油作为治疗皮肤疾病的新型治疗替代品具有潜力。为了开发基于纳米技术的现代制剂,人们投入了大量精力,使各种唇形科精油能够进行局部应用。本综述全面总结了过去十年中唇形科家族中各种精油的利用情况。它概述了这些油作为抗氧化剂、抗炎剂、伤口愈合剂、抗老化剂、抗黑色素生成剂和抗癌剂的用途,以及它们单独使用和与纳米粒子联合使用的情况。此外,该综述还探讨了它们在皮肤病专利中的潜在应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe3a/10607815/751259066fce/ijms-24-15279-g001.jpg

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