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Antiviral Activity of an Indole-Type Compound Derived from Natural Products, Identified by Virtual Screening by Interaction on Dengue Virus NS5 Protein.天然产物衍生吲哚类化合物通过与登革热病毒 NS5 蛋白相互作用的虚拟筛选鉴定的抗病毒活性。
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Applications of the Microscale Thermophoresis Binding Assay in COVID-19 Research.微尺度热泳结合分析在 COVID-19 研究中的应用。
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Anticoronavirus Evaluation of Antimicrobial Diterpenoids: Application of New Ferruginol Analogues.抗冠状病毒的抗菌二萜评估：新型土木香醇类似物的应用。
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In Silico and In Vitro Evaluation of Some Amidine Derivatives as Hit Compounds towards Development of Inhibitors against Coronavirus Diseases.计算机模拟和体外评估某些脒衍生物作为针对冠状病毒疾病抑制剂的先导化合物。
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CXCR4 Recognition by L- and D-Peptides Containing the Full-Length V3 Loop of HIV-1 gp120.CXCR4 的识别由包含全长 HIV-1 gp120 V3 环的 L-和 D-肽引起。
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Targeting the Human Influenza a Virus: The Methods, Limitations, and Pitfalls of Virtual Screening for Drug-like Candidates Including Scaffold Hopping and Compound Profiling.靶向人甲型流感病毒：药物样候选物的虚拟筛选方法、局限性和陷阱，包括骨架跃迁和化合物剖析。
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新型抗病毒药物：合成、分子模拟研究与生物学研究。

Novel Antiviral Agents: Synthesis, Molecular Modelling Studies and Biological Investigation.

机构信息

Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.

Bioinformatics Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.

出版信息

Viruses. 2023 Oct 2;15(10):2042. doi: 10.3390/v15102042.

DOI:10.3390/v15102042
PMID:37896819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10612019/
Abstract

Representing more than 20% of all deaths occurring worldwide, infectious diseases remain one of the main factors in both human and animal morbidity and mortality [...].

摘要

传染病导致的死亡占全球总死亡人数的 20%以上，仍是造成人类和动物发病和死亡的主要因素之一[... ]。