[Effectiveness of legalon and essentiale in a tetracycline-induced liver lesion].

It was shown in the experiments with albino rats that legalon and essentiale had a pronounced hepatoprotective effect in tetracycline affections of the liver. They retarded the increase in the activity of alanine aminotransferase, aspartate aminotransferase and alkaline phosphatase in blood serum, prevented suppression of cholopoiesis by tetracycline and inhibited lipid peroxidation. The drugs may be used for prevention and treatment of tetracycline affections of the liver.