Ng M H, Chan K H, Kong Y C
Biochem Int. 1986 Sep;13(3):521-31.
The edible bird's nest extract from Collocalia spp. was found to contain a glycoprotein which could potentiate mitogenic response of human peripheral blood monocytes to stimulation with Concanavalin A or Phytohemagglutinin A. The potentiating effect of the extract was most marked at suboptimal mitogenic concentrations of these lectins, decreasing the 50% optimal concentration of Con A and PHA by 6- and 2.5- folds respectively. The potentiating effect was exerted early during the first 10 hours following stimulation with Con A. This potentiation activity was not dialysable, but it was stable to limited digestion with trypsin, alkaline pH and extraction with ether.
发现来自金丝燕属的食用燕窝提取物含有一种糖蛋白，该糖蛋白可增强人外周血单核细胞对伴刀豆球蛋白A或植物血凝素A刺激的促有丝分裂反应。提取物的增强作用在这些凝集素的亚最佳促有丝分裂浓度下最为显著，分别将伴刀豆球蛋白A和植物血凝素A的50%最佳浓度降低了6倍和2.5倍。增强作用在伴刀豆球蛋白A刺激后的最初10小时内早期发挥作用。这种增强活性不可透析，但对胰蛋白酶的有限消化、碱性pH和乙醚提取具有稳定性。
