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胆总管肉瘤样癌表现为无痛性黄疸。

Sarcomatoid carcinoma of the common bile duct presenting as painless jaundice.

机构信息

Gastroenterology, Dalhousie University, Halifax, Nova Scotia, Canada.

Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.

出版信息

BMJ Case Rep. 2023 Nov 9;16(11):e257167. doi: 10.1136/bcr-2023-257167.

Abstract

A woman in her 70s presented with painless jaundice and index biopsy of a common bile duct (CBD) mass obtained by endoscopic retrograde cholangiopancreatography was suspicious for malignant peripheral nerve sheath tumour. Treatment consisted of pancreaticoduodenectomy, and final pathology results were consistent with sarcomatoid carcinoma. Postoperative complications included pancreaticojejunal leak, surgical wound infection, bacteraemia, myocardial injury, and significant ulceration and stricturing of the oesophagus. 14 weeks post-pancreaticoduodenectomy, the patient was found to have a perforated viscus, gastroduodenal leak and diffuse small bowel ischaemia-the patient passed away following emergent laparotomy. We aim to add to the limited literature surrounding this rare CBD neoplasm.

摘要

一位 70 多岁的女性出现无痛性黄疸,经内镜逆行胰胆管造影术(ERCP)获取胆总管(CBD)肿块的索引活检,提示恶性周围神经鞘肿瘤。治疗包括胰十二指肠切除术,最终的病理结果与肉瘤样癌一致。术后并发症包括胰肠漏、手术部位感染、菌血症、心肌损伤以及食管严重溃疡和狭窄。胰十二指肠切除术后 14 周,患者发现有一个穿孔的内脏,胃十二指肠漏和弥漫性小肠缺血-在紧急剖腹手术后,患者去世。我们旨在增加有关这种罕见 CBD 肿瘤的有限文献。

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本文引用的文献

1
Carcinosarcoma of common bile duct: A case report.胆总管癌肉瘤:一例报告。
World J Gastrointest Oncol. 2023 Mar 15;15(3):562-570. doi: 10.4251/wjgo.v15.i3.562.
8
Sarcomatoid carcinoma of the common bile duct: A case report.胆管肉瘤样癌:一例报告。
Medicine (Baltimore). 2017 Jan;96(3):e5751. doi: 10.1097/MD.0000000000005751.
10
Carcinosarcoma of the bile duct: a case report and review of literature.胆管癌肉瘤:一例报告并文献复习
Hepatobiliary Surg Nutr. 2016 Feb;5(1):72-8. doi: 10.3978/j.issn.2304-3881.2015.06.09.

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