Ortiz-Mendoza Nancy, Martínez-Gordillo Martha Juana, Martínez-Ambriz Emmanuel, Basurto-Peña Francisco Alberto, González-Trujano María Eva, Aguirre-Hernández Eva
Laboratorio de Productos Naturales, Departamento de Ecología y Recursos Naturales, Facultad de Ciencias, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Posgrado en Ciencias Biológicas, Unidad de Posgrado, Ciudad Universitaria Coyoacán, Edificio D, 1° Piso, Circuito de Posgrados, Mexico City 04510, Mexico.
Plants (Basel). 2023 Nov 2;12(21):3752. doi: 10.3390/plants12213752.
Nepetoideae is the most diverse subfamily of Lamiaceae, and some species are well known for their culinary and medicinal uses. In recent years, there has been growing interest in the therapeutic properties of the species of this group regarding inflammatory illnesses. This study aims to collect information on traditional uses through ethnobotanical, pharmacological, and phytochemical information of the subfamily Nepetoideae related to inflammatory diseases. UNAM electronic resources were used to obtain the information. The analysis of the most relevant literature was compiled and organised in tables. From this, about 106 species of the subfamily are traditionally recognised to alleviate chronic pain associated with inflammation. Pharmacological studies have been carried out in vitro and in vivo on approximately 308 species belonging to the genera , , , , , , and . Phytochemical and pharmacological evaluations have been performed and mostly prepared as essential oil or high polarity extracts, whose secondary metabolites are mainly of a phenolic nature. Other interesting and explored metabolites are diterpenes from the abietane, clerodane, and kaurane type; however, they have only been described in some species of the genera and . This review reveals that the Nepetoideae subfamily is an important source for therapeutics of the inflammatory process.
荆芥亚科是唇形科中最多样化的亚科，一些物种因其烹饪和药用价值而闻名。近年来，人们对该类群物种在炎症性疾病方面的治疗特性越来越感兴趣。本研究旨在通过与炎症性疾病相关的荆芥亚科的民族植物学、药理学和植物化学信息，收集有关传统用途的信息。利用墨西哥国立自治大学的电子资源获取信息。对最相关的文献进行分析，并整理成表格。由此可知，该亚科约有106个物种在传统上被认为可缓解与炎症相关的慢性疼痛。已对属于 、 、 、 、 、 和 属的约308个物种进行了体外和体内药理学研究。已经进行了植物化学和药理学评估，大多制备成精油或高极性提取物，其次生代谢产物主要为酚类性质。其他有趣且已被研究的代谢产物是枞烷型、克罗烷型和贝壳杉烷型二萜；然而，它们仅在 和 属的一些物种中被描述过。本综述表明，荆芥亚科是炎症过程治疗的重要来源。
