Li Junxiao, Zhong Qiongqiong, Yuan Shixiang, Zhu Feng
Central Laboratory, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Departments of Public Health and Preventive Medicine, Jinan University, Guangzhou, China.
Front Cardiovasc Med. 2024 Apr 26;11:1339910. doi: 10.3389/fcvm.2024.1339910. eCollection 2024.
High systolic blood pressure (HSBP) is severely related to stroke, although the global burden of stroke associated with HSBP needs to be understood.
Data derived from the Global Burden of Disease, Injuries, and Risk Factors Study were used to analyze deaths, disability-adjusted life years (DALYs), age-standardized rates of mortality (ASMR), age-standardized rates of DALY (ASDR), and estimated annual percentage change (EAPC).
Globally, 52.57% of deaths and 55.54% of DALYs from stroke were attributable to HSBP in 2019, with higher levels in men; the ASMRs and ASDRs in 1990-2019 experienced a decline of 34.89% and 31.71%, respectively, with the highest ASMR- and ASDR-related EAPCs in women. The middle socio-demographic index (SDI) regions showed the most numbers of deaths and DALYs in 2019 and 1990, with a decline in ASMR and ASDR; East Asia shared over 33% of global deaths and DALYs; Central Asia shared the highest ASMR and ASDR; high-income Asia Pacific experienced the highest decline in the ASMR- and ASDR-related EAPCs. Central and Southeast Asia had the highest percentages for deaths and DALYs, respectively, with more ASMR in high-middle SDI; the SDI and human development index were negatively associated with ASMR/ASDR and ASMR/ASDR-related EAPCs in 2019.
Global deaths and DALYs of stroke attributable to HSBP but none of their age-standardized rates have been on the rise over the past three decades; its disease burden focused especially on men aged 70 years and older in East, Central, and Southeast Asia, and the middle to high SDI regions.
尽管需要了解与高收缩压（HSBP）相关的中风的全球负担，但高收缩压与中风密切相关。
使用来自全球疾病、伤害和风险因素研究的数据来分析死亡人数、伤残调整生命年（DALYs）、年龄标准化死亡率（ASMR）、年龄标准化DALY率（ASDR）以及估计的年度百分比变化（EAPC）。
2019年，全球中风死亡人数的52.57%和DALYs的55.54%可归因于HSBP，男性比例更高；1990 - 2019年，ASMR和ASDR分别下降了34.89%和31.71%，女性中与ASMR和ASDR相关的EAPC最高。2019年和1990年，社会人口指数（SDI）中等地区的死亡人数和DALYs最多，ASMR和ASDR有所下降；东亚占全球死亡人数和DALYs的比例超过33%；中亚的ASMR和ASDR最高；高收入亚太地区与ASMR和ASDR相关的EAPC下降幅度最大。中亚和东南亚的死亡人数和DALYs百分比分别最高，高中等SDI地区的ASMR更高；2019年，SDI和人类发展指数与ASMR/ASDR以及与ASMR/ASDR相关的EAPC呈负相关。
过去三十年中，全球因HSBP导致的中风死亡人数和DALYs均未上升，但其年龄标准化率也未上升；其疾病负担尤其集中在东亚、中亚和东南亚70岁及以上的男性以及中等至高SDI地区。
