Joya Musa, Nedaie Hassan Ali, Geraily Ghazale, Rezaei Hadi, Bromand Awaz, Ghorbani Mahdi, Sheikhzadeh Peyman
Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran, Iran.
Department of Radiology, Kabul University of Medical Sciences, Kabul, Afghanistan.
J Med Phys. 2023 Jul-Sep;48(3):268-273. doi: 10.4103/jmp.jmp_41_23. Epub 2023 Sep 18.
According to the revised Task Group number 43 recommendations, a brachytherapy source must be validated against a similar or identical source before its clinical application. The purpose of this investigation is to verify the dosimetric data of the high dose rate (HDR) BEBIG Ir source (Ir2.A85-2).
The HDR Ir encapsulated seed was simulated and its main dosimetric data were calculated using Geant4 Application for Tomographic Emission (GATE) simulation code. Cubic cells were used for the calculation of dose rate constant and radial dose function while for anisotropy function ring cells were used. DoseActors were simulated and attached to the respective cells to obtain the required data.
The dose rate constant was obtained as 1.098 ± 0.003 cGy.h - .U - , differing by 1.0% from the reference value reported by Granero . Similarly, the calculated values for radial dose and anisotropy functions presented good agreement with the results obtained by Granero .
The results of this study suggest that the GATE Monte Carlo code is a valid toolkit for benchmarking brachytherapy sources and can be used for brachytherapy simulation-based studies and verification of brachytherapy treatment planning systems.
根据第43工作组的修订建议，近距离放射治疗源在临床应用前必须对照相似或相同的源进行验证。本研究的目的是验证高剂量率（HDR）BEBIG铱源（Ir2.A85 - 2）的剂量学数据。
对HDR铱封装籽源进行模拟，并使用用于断层发射的Geant4应用程序（GATE）模拟代码计算其主要剂量学数据。使用立方体细胞计算剂量率常数和径向剂量函数，而对于各向异性函数则使用环形细胞。模拟剂量作用体并将其附着到相应细胞上以获取所需数据。
获得的剂量率常数为1.098±0.003 cGy·h⁻¹·U⁻¹，与Granero报告的参考值相差1.0%。同样，径向剂量和各向异性函数的计算值与Granero获得的结果具有良好的一致性。
本研究结果表明，GATE蒙特卡罗代码是用于近距离放射治疗源基准测试的有效工具包，可用于基于近距离放射治疗模拟的研究以及近距离放射治疗治疗计划系统的验证。
