Lazarus Ethan, Bays Harold Edward
Diplomate American Board of Obesity Medicine, Diplomate American Board of Family Medicine, President Obesity Medicine Association (2021- 2022); Delegate American Medical Association, Clinical Nutrition Center 5995 Greenwood Plaza Blvd, Ste 150, Greenwood Village, CO 80111.
Diplomate of American Board of Obesity Medicine, Medical Director/President Louisville Metabolic and Atherosclerosis Research Center, Clinical Associate Professor/University of Louisville Medical School, 3288 Illinois Avenue, Louisville, KY, 40213, USA.
Obes Pillars. 2022 Jul 5;3:100026. doi: 10.1016/j.obpill.2022.100026. eCollection 2022 Sep.
This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) provides an overview of cancer and increased body fat.
The scientific information for this CPS is based upon published scientific citations, clinical perspectives of OMA authors, and peer review by the Obesity Medicine Association leadership.
Topics include the increased risk of cancers among patients with obesity, cancer risk factor population-attributable fractions, genetic and epigenetic links between obesity and cancer, adiposopathic and mechanistic processes accounting for increased cancer risk among patients with obesity, the role of oxidative stress, and obesity-related cancers based upon Mendelian randomization and observational studies. Other topics include nutritional and physical activity principles for patients with obesity who either have cancer or are at risk for cancer, and preventive care as it relates to cancer and obesity.
Obesity is the second most common preventable cause of cancer and may be the most common preventable cause of cancer among nonsmokers. This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) on cancer is one of a series of OMA CPSs designed to assist clinicians in the care of patients with the disease of obesity. Patients with obesity are at greater risk of developing certain types of cancers, and treatment of obesity may influence the risk, onset, progression, and recurrence of cancer in patients with obesity.
本肥胖医学协会（OMA）临床实践声明（CPS）概述了癌症与体脂增加的相关情况。
本CPS的科学信息基于已发表的科学文献引用、OMA作者的临床观点以及肥胖医学协会领导层的同行评审。
主题包括肥胖患者患癌风险增加、癌症风险因素的人群归因分数、肥胖与癌症之间的遗传和表观遗传联系、肥胖患者癌症风险增加的脂肪病理和机制过程、氧化应激的作用以及基于孟德尔随机化和观察性研究的肥胖相关癌症。其他主题包括针对患有癌症或有癌症风险的肥胖患者的营养和身体活动原则，以及与癌症和肥胖相关的预防保健。
肥胖是第二大最常见的可预防癌症病因，可能是不吸烟者中最常见的可预防癌症病因。本肥胖医学协会（OMA）关于癌症的临床实践声明（CPS）是OMA CPS系列之一，旨在帮助临床医生护理肥胖症患者。肥胖患者患某些类型癌症的风险更高，肥胖症的治疗可能会影响肥胖患者癌症的风险、发病、进展和复发。
