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植物代谢组学:当前进展与未来展望

Plant Metabolomics: Current Initiatives and Future Prospects.

作者信息

Manickam Sudha, Rajagopalan Veera Ranjani, Kambale Rohit, Rajasekaran Raghu, Kanagarajan Selvaraju, Muthurajan Raveendran

机构信息

Department of Plant Biotechnology, Centre for Plant Molecular Biology and Biotechnology, Tamil Nadu Agricultural University, Coimbatore 641003, India.

Department of Plant Breeding, Swedish University of Agricultural Sciences, P.O. Box 190, 234 22 Lomma, Sweden.

出版信息

Curr Issues Mol Biol. 2023 Nov 8;45(11):8894-8906. doi: 10.3390/cimb45110558.

Abstract

Plant metabolomics is a rapidly advancing field of plant sciences and systems biology. It involves comprehensive analyses of small molecules (metabolites) in plant tissues and cells. These metabolites include a wide range of compounds, such as sugars, amino acids, organic acids, secondary metabolites (e.g., alkaloids and flavonoids), lipids, and more. Metabolomics allows an understanding of the functional roles of specific metabolites in plants' physiology, development, and responses to biotic and abiotic stresses. It can lead to the identification of metabolites linked with specific traits or functions. Plant metabolic networks and pathways can be better understood with the help of metabolomics. Researchers can determine how plants react to environmental cues or genetic modifications by examining how metabolite profiles change under various crop stages. Metabolomics plays a major role in crop improvement and biotechnology. Integrating metabolomics data with other omics data (genomics, transcriptomics, and proteomics) provides a more comprehensive perspective of plant biology. This systems biology approach enables researchers to understand the complex interactions within organisms.

摘要

植物代谢组学是植物科学和系统生物学中一个快速发展的领域。它涉及对植物组织和细胞中的小分子(代谢物)进行全面分析。这些代谢物包括多种化合物,如糖类、氨基酸、有机酸、次生代谢物(如生物碱和黄酮类化合物)、脂质等等。代谢组学有助于了解特定代谢物在植物生理、发育以及对生物和非生物胁迫反应中的功能作用。它能够鉴定与特定性状或功能相关的代谢物。借助代谢组学,可以更好地理解植物代谢网络和途径。研究人员通过检查不同作物生长阶段代谢物谱的变化,能够确定植物对环境信号或基因修饰的反应方式。代谢组学在作物改良和生物技术中发挥着重要作用。将代谢组学数据与其他组学数据(基因组学、转录组学和蛋白质组学)整合,能提供关于植物生物学更全面的视角。这种系统生物学方法使研究人员能够理解生物体内部的复杂相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37a0/10670879/98e9cc9304de/cimb-45-00558-g002.jpg

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