鼠伤寒沙门氏菌H1群R因子对抗菌治疗的毒力及感染反应的影响。
Effect of a Salmonella group H1 R factor on virulence and response of infections to antimicrobial therapy.
作者信息
Butler T, Shuster C W, Franco A
出版信息
Antimicrob Agents Chemother. 1979 Mar;15(3):478-80. doi: 10.1128/AAC.15.3.478.
Abstract
A group H1 R factor encoding resistance to chloramphenicol, streptomycin, sulfonamide, and tetracycline was transferred into Salmonella typhimurium LT-2. The virulence of LT-2 for mice, as assessed by intraperitoneal 50% lethal dose and the number of organisms in the spleen, was not affected by the R factor. On the other hand, the R factor conferred resistance in mouse infections to therapy with chloramphenicol and trimethoprim plus sulfamethoxazole.
摘要
一种编码对氯霉素、链霉素、磺胺类药物和四环素耐药性的H1型R因子被转移到鼠伤寒沙门氏菌LT-2中。通过腹腔注射50%致死剂量和脾脏中的细菌数量评估，LT-2对小鼠的毒力不受R因子的影响。另一方面，R因子使小鼠感染时对氯霉素以及甲氧苄啶加磺胺甲恶唑的治疗产生耐药性。
相似文献
1
Effect of a Salmonella group H1 R factor on virulence and response of infections to antimicrobial therapy.鼠伤寒沙门氏菌H1群R因子对抗菌治疗的毒力及感染反应的影响。
Antimicrob Agents Chemother. 1979 Mar;15(3):478-80. doi: 10.1128/AAC.15.3.478.
2
Characterization of Virulence-Associated Genes, Antimicrobial Resistance Genes, and Class 1 Integrons in Salmonella enterica serovar Typhimurium Isolates from Chicken Meat and Humans in Egypt.埃及鸡肉和人类来源的肠炎沙门氏菌鼠伤寒血清型分离株中毒力相关基因、抗菌耐药基因及1类整合子的特征分析
Foodborne Pathog Dis. 2016 Jun;13(6):281-8. doi: 10.1089/fpd.2015.2097. Epub 2016 Mar 15.
3
pJT2: unusual H1 plasmid in a highly virulent lactose-positive and chloramphenicol-resistant Salmonella typhimurium strain from calves.
Antimicrob Agents Chemother. 1980 Sep;18(3):480-2. doi: 10.1128/AAC.18.3.480.
4
Antimicrobial Resistance in Salmonella in the United States from 1948 to 1995.1948年至1995年美国沙门氏菌的抗菌药物耐药性
Antimicrob Agents Chemother. 2016 Mar 25;60(4):2567-71. doi: 10.1128/AAC.02536-15. Print 2016 Apr.
5
Prevalence of R-type ACSSuT in strains of Salmonella serovar Typhimurium DT193 isolated from human infections in Brazil.巴西人类感染伤寒血清型鼠伤寒沙门氏菌 DT193 菌株中 R 型 ACSSuT 的流行情况。
Rev Panam Salud Publica. 2011 Jun;29(6):387-92.
6
Trimethoprim-resistance plasmids and transposons in Salmonella.沙门氏菌中的甲氧苄啶抗性质粒和转座子。
Lancet. 1978 Dec 2;2(8101):1194-5. doi: 10.1016/s0140-6736(78)92171-2.
7
Life-threatening infantile diarrhea from fluoroquinolone-resistant Salmonella enterica typhimurium with mutations in both gyrA and parC.由同时具有gyrA和parC突变的耐氟喹诺酮鼠伤寒沙门氏菌引起的危及生命的婴儿腹泻。
Emerg Infect Dis. 2003 Feb;9(2):255-7. doi: 10.3201/eid0902.020185.
8
Antimicrobial resistance and R-factor transfer among isolates of Salmonella in the northeastern United States: a comparison of human and animal isolates.
J Infect Dis. 1975 Dec;132(6):617-22. doi: 10.1093/infdis/132.6.617.
9
A multi-drug resistant Salmonella Typhimurium ST213 human-invasive strain (33676) containing the bla CMY-2 gene on an IncF plasmid is attenuated for virulence in BALB/c mice.一种多药耐药性鼠伤寒沙门氏菌ST213人侵袭性菌株（33676），其在IncF质粒上携带bla CMY-2基因，在BALB/c小鼠中毒力减弱。
BMC Microbiol. 2016 Feb 9;16:18. doi: 10.1186/s12866-016-0633-7.
10
The genetics of Salmonella genomic island 1.沙门氏菌基因组岛1的遗传学
Microbes Infect. 2006 Jun;8(7):1915-22. doi: 10.1016/j.micinf.2005.12.028. Epub 2006 Mar 27.
引用本文的文献
1
Treatment of experimental Salmonella typhimurium infection with mecillinam and ampicillin.用美西林和氨苄西林治疗实验性鼠伤寒沙门氏菌感染。
Antimicrob Agents Chemother. 1981 Feb;19(2):328-31. doi: 10.1128/AAC.19.2.328.
2
Comparative efficacies of ceftriaxone, moxalactam, and ampicillin in experimental Salmonella typhimurium infection.头孢曲松、莫西酰胺和氨苄西林在鼠伤寒沙门氏菌实验性感染中的比较疗效
Antimicrob Agents Chemother. 1982 Aug;22(2):312-5. doi: 10.1128/AAC.22.2.312.
3
Treatment of experimental Salmonella typhimurium infection in mice with fleroxacin.用氟罗沙星治疗小鼠实验性鼠伤寒沙门氏菌感染。
Antimicrob Agents Chemother. 1988 May;32(5):791-2. doi: 10.1128/AAC.32.5.791.
本文引用的文献
1
Some physiopathological parameters of natural resistance to infection in murine salmonellosis.鼠伤寒沙门氏菌病天然抗感染的一些生理病理参数。
J Exp Med. 1959 Jul 1;110(1):9-26. doi: 10.1084/jem.110.1.9.
2
Infection-immunity in experimental salmonellosis.实验性沙门氏菌病中的感染免疫
J Exp Med. 1966 Oct 1;124(4):601-19. doi: 10.1084/jem.124.4.601.
3
Host-parasite relations in mouse typhoid.小鼠伤寒中的宿主-寄生虫关系。
J Exp Med. 1966 Oct 1;124(4):573-83. doi: 10.1084/jem.124.4.573.
4
Trimethoprim, a sulphonamide potentiator.甲氧苄啶，一种磺胺增效剂。
Br J Pharmacol Chemother. 1968 May;33(1):72-90. doi: 10.1111/j.1476-5381.1968.tb00475.x.
5
Chloramphenicol-resistant strains of Salmonella typhosa.伤寒沙门氏菌的氯霉素抗性菌株。
N Engl J Med. 1972 Jun 1;286(22):1220.
6
Mechanisms of acquired resistance in mouse typhoid.小鼠伤寒获得性耐药机制。
J Exp Med. 1966 Oct 1;124(4):585-600. doi: 10.1084/jem.124.4.585.
7
Salmonella typhi resistant to chloramphenicol, ampicillin, and other antimicrobial agents: strains isolated during an extensive typhoid fever epidemic in Mexico.对氯霉素、氨苄西林和其他抗菌药物耐药的伤寒沙门氏菌：在墨西哥一次广泛的伤寒热疫情期间分离出的菌株
Antimicrob Agents Chemother. 1973 Dec;4(6):597-601. doi: 10.1128/AAC.4.6.597.
8
An epidemic-associated episome?一种与流行病相关的附加体？
J Infect Dis. 1972 Aug;126(2):215-8. doi: 10.1093/infdis/126.2.215.
9
Amoxicillin in the treatment of typhoid fever due to chloramphenicol-resistance Salmonella typhi.阿莫西林治疗耐氯霉素伤寒杆菌所致的伤寒热。
J Infect Dis. 1974 Jun;129(0):suppl:S219-21. doi: 10.1093/infdis/129.supplement_2.s219.
10
Chloramphenicol-resistant typhoid fever in Vietnam associated with R factor.越南与R因子相关的耐氯霉素伤寒热
Lancet. 1973 Nov 3;302(7836):983-5. doi: 10.1016/s0140-6736(73)91086-6.
Zotero 插件