Department of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, Florida Campus, University of South Africa, Private Bag X6, Florida 1710, South Africa.
Molecules. 2023 Nov 24;28(23):7759. doi: 10.3390/molecules28237759.
Hochst. ex. A. DC is widely distributed throughout Africa and around the world. It is utilized ethnobotanically to treat fevers, wounds, malaria, diabetes mellitus, and other diseases. This review aims to provide an exhaustive overview of the traditional uses, pharmacology, and phytochemical analysis of , with the objective of identifying its therapeutic potential for further research. Scientific resources, including Google Scholar, Science Direct, Web of Science, Pub Med, and Scopus, were used to find pertinent data on . Secondary metabolites tentatively identified from this species were primarily terpenoids, naphthoquinones, phenolics, and coumarins. has been reported to demonstrate pharmacological activities, including antimicrobial, antiproliferative, antiparasitic, antioxidant, anti-inflammatory, antiviral, anti-hypersensitivity, and antidiabetic properties. The phytochemicals and extracts from have been reported to have some pharmacological effects in in vivo studies and were not toxic to the animal models that were utilized. The information reported in this review provides researchers with a comprehensive summary of the current research status of this medicinal plant and a guide for further investigation.
大戟属植物广泛分布于非洲和世界各地。它在传统医学中被用于治疗发热、创伤、疟疾、糖尿病等疾病。本综述旨在全面概述大戟属植物的传统用途、药理学和植物化学分析,旨在确定其治疗潜力,以供进一步研究。科学资源,包括 Google Scholar、Science Direct、Web of Science、Pub Med 和 Scopus,被用于查找关于大戟属植物的相关数据。从该物种中初步鉴定的次生代谢产物主要为萜类、萘醌类、酚类和香豆素类。已报道大戟属植物具有多种药理学活性,包括抗菌、抗增殖、抗寄生虫、抗氧化、抗炎、抗病毒、抗超敏反应和抗糖尿病特性。来自大戟属植物的植物化学物质和提取物已被报道在体内研究中具有一些药理作用,并且对所使用的动物模型没有毒性。本综述中报告的大戟属植物信息为研究人员提供了该药用植物当前研究状况的全面总结,并为进一步研究提供了指导。