牙周病学中的大麻素：我们目前的进展如何？
Cannabinoids in Periodontology: Where Are We Now?
作者信息
Carmona Rendón Yésica, Garzón Hernán Santiago, Bueno-Silva Bruno, Arce Roger M, Suárez Lina Janeth
机构信息
Departamento de Ciencias Básicas y Medicina Oral, Facultad de Odontología, Universidad Nacional de Colombia, Bogotá 111321, Colombia.
Programa de Doctorado en Ingeniería, Facultad de Ingeniería, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
出版信息
Antibiotics (Basel). 2023 Nov 30;12(12):1687. doi: 10.3390/antibiotics12121687.
INTRODUCTION
Cannabinoids are a well-documented treatment modality for various immune and inflammatory diseases, including asthma, chronic obstructive pulmonary disease, Crohn's disease, arthritis, multiple sclerosis, and a range of neurodegenerative conditions. However, limited information is available regarding the therapeutic potential of cannabinoids in treating periodontal disease.
OBJECTIVE
The objective of this study is to analyze the current evidence on the antibacterial and immunomodulatory effects of cannabis and its role in the healing and regeneration processes within periodontal tissues.
RESULTS
This review discusses the potential role of cannabinoids in restoring periodontal tissue homeostasis.
CONCLUSIONS
The examination of the endocannabinoid system and the physiological effects of cannabinoids in the periodontium suggests that they possess immunomodulatory and antibacterial properties, which could potentially promote proper tissue healing and regeneration.
引言
大麻素是一种有充分文献记载的治疗多种免疫和炎症性疾病的方法，包括哮喘、慢性阻塞性肺疾病、克罗恩病、关节炎、多发性硬化症以及一系列神经退行性疾病。然而，关于大麻素在治疗牙周病方面的治疗潜力的信息有限。
目的
本研究的目的是分析关于大麻及其在牙周组织愈合和再生过程中的作用的抗菌和免疫调节作用的现有证据。
结果
本综述讨论了大麻素在恢复牙周组织稳态中的潜在作用。
结论
对内源性大麻素系统以及大麻素在牙周组织中的生理作用的研究表明，它们具有免疫调节和抗菌特性，这可能潜在地促进适当的组织愈合和再生。
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