Jonsson L, Stiernstedt G, Thomander L
Arch Otolaryngol Head Neck Surg. 1987 Mar;113(3):303-6. doi: 10.1001/archotol.1987.01860030079013.
An enzyme-linked immunosorbent assay was applied to serum samples of 94 patients diagnosed as having Bell's palsy: they were studied throughout two consecutive years in an attempt to establish serologic evidence of a tick-borne spirochetal infection. A strain of Borrelia spirochetes, isolated from Swedish Ixodes ricinus ticks, was used as an antigen, and separate estimations of spirochetal IgG and IgM antibodies were made; serum samples with titers above the 95th-percentile level of 120 healthy individuals were considered positive. Thirteen percent of the patients' serum samples were IgG-positive, 3% were positive for IgM, and 3% were positive for both IgG and IgM. A twofold or greater increase of IgG titers was found in 6%. All the patients who were seropositive experienced the onset of palsy during the period from July to December.
对94例被诊断为贝尔麻痹的患者的血清样本进行了酶联免疫吸附测定:连续两年对他们进行研究,试图建立蜱传螺旋体感染的血清学证据。从瑞典蓖麻硬蜱分离出的一种疏螺旋体菌株用作抗原,分别对螺旋体IgG和IgM抗体进行了测定;滴度高于120名健康个体第95百分位数水平的血清样本被视为阳性。13%的患者血清样本IgG呈阳性,3%的患者IgM呈阳性,3%的患者IgG和IgM均呈阳性。6%的患者IgG滴度升高两倍或更高。所有血清阳性的患者均在7月至12月期间出现麻痹症状。