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贝尔麻痹患者的蜱传疏螺旋体感染

Tick-borne Borrelia infection in patients with Bell's palsy.

作者信息

Jonsson L, Stiernstedt G, Thomander L

出版信息

Arch Otolaryngol Head Neck Surg. 1987 Mar;113(3):303-6. doi: 10.1001/archotol.1987.01860030079013.

DOI:10.1001/archotol.1987.01860030079013
PMID:3814376
Abstract

An enzyme-linked immunosorbent assay was applied to serum samples of 94 patients diagnosed as having Bell's palsy: they were studied throughout two consecutive years in an attempt to establish serologic evidence of a tick-borne spirochetal infection. A strain of Borrelia spirochetes, isolated from Swedish Ixodes ricinus ticks, was used as an antigen, and separate estimations of spirochetal IgG and IgM antibodies were made; serum samples with titers above the 95th-percentile level of 120 healthy individuals were considered positive. Thirteen percent of the patients' serum samples were IgG-positive, 3% were positive for IgM, and 3% were positive for both IgG and IgM. A twofold or greater increase of IgG titers was found in 6%. All the patients who were seropositive experienced the onset of palsy during the period from July to December.

摘要

对94例被诊断为贝尔麻痹的患者的血清样本进行了酶联免疫吸附测定:连续两年对他们进行研究,试图建立蜱传螺旋体感染的血清学证据。从瑞典蓖麻硬蜱分离出的一种疏螺旋体菌株用作抗原,分别对螺旋体IgG和IgM抗体进行了测定;滴度高于120名健康个体第95百分位数水平的血清样本被视为阳性。13%的患者血清样本IgG呈阳性,3%的患者IgM呈阳性,3%的患者IgG和IgM均呈阳性。6%的患者IgG滴度升高两倍或更高。所有血清阳性的患者均在7月至12月期间出现麻痹症状。

相似文献

1
Tick-borne Borrelia infection in patients with Bell's palsy.贝尔麻痹患者的蜱传疏螺旋体感染
Arch Otolaryngol Head Neck Surg. 1987 Mar;113(3):303-6. doi: 10.1001/archotol.1987.01860030079013.
2
Erythema chronicum migrans Afzelius and acrodermatitis chronica atrophicans. Early and late manifestations of Ixodes ricinus-borne Borrelia spirochetes.阿费利乌斯慢性游走性红斑和慢性萎缩性肢端皮炎。蓖麻硬蜱传播的疏螺旋体的早期和晚期表现。
Acta Derm Venereol Suppl (Stockh). 1985;118:1-63.
3
Tick-borne Borrelia infection in Sweden.瑞典的蜱传疏螺旋体感染
Scand J Infect Dis Suppl. 1985;45:1-70. doi: 10.3109/inf.1985.17.suppl-45.01.
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Tick-borne borreliosis and facial palsy.蜱传疏螺旋体病与面神经麻痹。
Acta Otolaryngol. 1988 Jan-Feb;105(1-2):100-7. doi: 10.3109/00016488809119451.
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Facial palsy in Bannwarth's syndrome: a tick-borne spirochetosis.班诺瓦特综合征中的面神经麻痹:一种蜱传螺旋体病。
Arch Otolaryngol. 1985 Aug;111(8):557. doi: 10.1001/archotol.1985.00800100105019.
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Serum and cerebrospinal fluid examinations in the diagnosis of Borrelia infection in Bell's palsy.
Acta Otolaryngol. 1990 Nov-Dec;110(5-6):421-6. doi: 10.3109/00016489009107464.
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Joint and bone involvement in Swedish patients with Ixodes ricinus-borne Borrelia infection.瑞典蓖麻硬蜱传播的疏螺旋体感染患者的关节和骨骼受累情况
Zentralbl Bakteriol Mikrobiol Hyg A. 1986 Dec;263(1-2):275-84. doi: 10.1016/s0176-6724(86)80132-8.
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Peripheral facial palsy caused by the Borrelia spirochete.由疏螺旋体引起的周围性面神经麻痹。
Acta Otolaryngol. 1989 Nov-Dec;108(5-6):424-30. doi: 10.3109/00016488909125548.
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Anti-Borrelia burgdorferi antibodies in patients with facial paralysis.面瘫患者体内的抗伯氏疏螺旋体抗体
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[Borreliae as possible antagonists of tick-borne encephalitis virus: parasitologic and clinical aspects].[疏螺旋体作为蜱传脑炎病毒的潜在拮抗物:寄生虫学及临床方面]
Med Parazitol (Mosk). 2001 Jul-Sep(3):3-11.

引用本文的文献

1
Immunoglobulin M immunoblot for diagnosis of Borrelia burgdorferi infection in patients with acute facial palsy.用于诊断急性面神经麻痹患者莱姆病螺旋体感染的免疫球蛋白M免疫印迹法
J Clin Microbiol. 1996 Aug;34(8):2033-5. doi: 10.1128/jcm.34.8.2033-2035.1996.
2
Anti-Borrelia burgdorferi antibodies in patients with facial paralysis.面瘫患者体内的抗伯氏疏螺旋体抗体
Eur Arch Otorhinolaryngol. 1993;249(8):488-91. doi: 10.1007/BF00168862.