• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

用于生物电子传感器的有机混合离子-电子导体：材料与运行机制

Organic Mixed Ionic-Electronic Conductors for Bioelectronic Sensors: Materials and Operation Mechanisms.

作者信息

Kim Hyunwook, Won Yousang, Song Hyun Woo, Kwon Yejin, Jun Minsang, Oh Joon Hak

机构信息

School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea.

出版信息

Adv Sci (Weinh). 2024 Jul;11(27):e2306191. doi: 10.1002/advs.202306191. Epub 2023 Dec 26.

DOI:10.1002/advs.202306191
PMID:38148583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11251567/
Abstract

The field of organic mixed ionic-electronic conductors (OMIECs) has gained significant attention due to their ability to transport both electrons and ions, making them promising candidates for various applications. Initially focused on inorganic materials, the exploration of mixed conduction has expanded to organic materials, especially polymers, owing to their advantages such as solution processability, flexibility, and property tunability. OMIECs, particularly in the form of polymers, possess both electronic and ionic transport functionalities. This review provides an overview of OMIECs in various aspects covering mechanisms of charge transport including electronic transport, ionic transport, and ionic-electronic coupling, as well as conducting/semiconducting conjugated polymers and their applications in organic bioelectronics, including (multi)sensors, neuromorphic devices, and electrochromic devices. OMIECs show promise in organic bioelectronics due to their compatibility with biological systems and the ability to modulate electronic conduction and ionic transport, resembling the principles of biological systems. Organic electrochemical transistors (OECTs) based on OMIECs offer significant potential for bioelectronic applications, responding to external stimuli through modulation of ionic transport. An in-depth review of recent research achievements in organic bioelectronic applications using OMIECs, categorized based on physical and chemical stimuli as well as neuromorphic devices and circuit applications, is presented.

摘要

有机混合离子 - 电子导体（OMIECs）领域因其能够同时传输电子和离子而备受关注，这使其成为各种应用的有前途的候选材料。最初专注于无机材料，由于其诸如溶液可加工性、柔韧性和性能可调性等优点，混合传导的探索已扩展到有机材料，特别是聚合物。OMIECs，特别是聚合物形式，具有电子和离子传输功能。本综述概述了OMIECs在各个方面的情况，涵盖电荷传输机制，包括电子传输、离子传输和离子 - 电子耦合，以及导电/半导体共轭聚合物及其在有机生物电子学中的应用，包括（多）传感器、神经形态器件和电致变色器件。OMIECs因其与生物系统的兼容性以及调节电子传导和离子传输的能力，类似于生物系统的原理，在有机生物电子学中显示出前景。基于OMIECs的有机电化学晶体管（OECTs）在生物电子应用中具有巨大潜力，通过调节离子传输对外部刺激做出响应。本文对使用OMIECs的有机生物电子应用的近期研究成果进行了深入综述，根据物理和化学刺激以及神经形态器件和电路应用进行了分类。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/916658db1336/ADVS-11-2306191-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/c7f78722ab24/ADVS-11-2306191-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/64e9e596f994/ADVS-11-2306191-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/fd8f9089cb2a/ADVS-11-2306191-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/3aa4ea0afe69/ADVS-11-2306191-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/319720f0ae89/ADVS-11-2306191-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/976f3286804c/ADVS-11-2306191-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/f6cc339c80d0/ADVS-11-2306191-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/ef6e1a0d5b70/ADVS-11-2306191-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/78abce47f977/ADVS-11-2306191-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/3b9a6109c5e5/ADVS-11-2306191-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/3bd97419b610/ADVS-11-2306191-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/b1a601af7c73/ADVS-11-2306191-g021.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/f8faa9abd4b9/ADVS-11-2306191-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/916658db1336/ADVS-11-2306191-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/c7f78722ab24/ADVS-11-2306191-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/64e9e596f994/ADVS-11-2306191-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/fd8f9089cb2a/ADVS-11-2306191-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/3aa4ea0afe69/ADVS-11-2306191-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/319720f0ae89/ADVS-11-2306191-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/976f3286804c/ADVS-11-2306191-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/f6cc339c80d0/ADVS-11-2306191-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/ef6e1a0d5b70/ADVS-11-2306191-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/78abce47f977/ADVS-11-2306191-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/3b9a6109c5e5/ADVS-11-2306191-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/3bd97419b610/ADVS-11-2306191-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/b1a601af7c73/ADVS-11-2306191-g021.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/f8faa9abd4b9/ADVS-11-2306191-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238a/11251567/916658db1336/ADVS-11-2306191-g005.jpg

相似文献

1
Organic Mixed Ionic-Electronic Conductors for Bioelectronic Sensors: Materials and Operation Mechanisms.用于生物电子传感器的有机混合离子-电子导体：材料与运行机制
Adv Sci (Weinh). 2024 Jul;11(27):e2306191. doi: 10.1002/advs.202306191. Epub 2023 Dec 26.
2
The effect of side chain engineering on conjugated polymers in organic electrochemical transistors for bioelectronic applications.侧链工程对用于生物电子应用的有机电化学晶体管中共轭聚合物的影响。
J Mater Chem C Mater. 2022 Jan 7;10(7):2314-2332. doi: 10.1039/d1tc05229b. eCollection 2022 Feb 17.
3
Mixed Ionic-Electronic Conduction, a Multifunctional Property in Organic Conductors.混合离子-电子传导，有机导体中的一种多功能特性。
Adv Mater. 2022 May;34(21):e2110406. doi: 10.1002/adma.202110406. Epub 2022 Apr 18.
4
Molecular Design Strategies toward Improvement of Charge Injection and Ionic Conduction in Organic Mixed Ionic-Electronic Conductors for Organic Electrochemical Transistors.朝向改善有机电化学晶体管中有机混合离子-电子导体的电荷注入和离子传导的分子设计策略。
Chem Rev. 2022 Feb 23;122(4):4325-4355. doi: 10.1021/acs.chemrev.1c00266. Epub 2021 Dec 13.
5
Organic Mixed Ionic-Electronic Conductors Based on Tunable and Functional Poly(3,4-ethylenedioxythiophene) Copolymers.基于可调控功能聚（3,4-亚乙基二氧噻吩）共聚物的有机混合离子-电子导体
ACS Appl Mater Interfaces. 2024 Jun 5;16(22):28969-28979. doi: 10.1021/acsami.4c03229. Epub 2024 May 23.
6
A Semiconducting Two-Dimensional Polymer as an Organic Electrochemical Transistor Active Layer.一种作为有机电化学晶体管活性层的半导体二维聚合物。
Adv Mater. 2022 May;34(21):e2110703. doi: 10.1002/adma.202110703. Epub 2022 Apr 21.
7
Conjugated Polymers for Microwave Applications: Untethered Sensing Platforms and Multifunctional Devices.用于微波应用的共轭聚合物：无束缚传感平台和多功能器件
Adv Mater. 2022 Aug;34(33):e2202994. doi: 10.1002/adma.202202994. Epub 2022 Jul 15.
8
Ambipolar blend-based organic electrochemical transistors and inverters.基于双极性掺杂的有机电化学晶体管和逆变器。
Nat Commun. 2022 Sep 22;13(1):5548. doi: 10.1038/s41467-022-33264-2.
9
Adaptive Biosensing and Neuromorphic Classification Based on an Ambipolar Organic Mixed Ionic-Electronic Conductor.基于双极有机混合离子-电子导体的自适应生物传感和神经形态分类。
Adv Mater. 2022 May;34(20):e2200393. doi: 10.1002/adma.202200393. Epub 2022 Apr 17.
10
Organic mixed ionic-electronic conductors.有机混合离子-电子导体。
Nat Mater. 2020 Jan;19(1):13-26. doi: 10.1038/s41563-019-0435-z. Epub 2019 Aug 19.

引用本文的文献

1
Biomimetic microstructure design for ultrasensitive piezoionic mechanoreceptors in multimodal object recognition.用于多模态物体识别中超高灵敏度压离子机械感受器的仿生微结构设计
Nat Commun. 2025 Aug 30;16(1):8129. doi: 10.1038/s41467-025-63115-9.
2
Evolving Role of Conjugated Polymers in Nanoelectronics and Photonics.共轭聚合物在纳米电子学和光子学中的角色演变
Nanomicro Lett. 2025 Apr 24;17(1):230. doi: 10.1007/s40820-025-01748-7.
3
A Solution-Based Deposition Method Enabling Pigment Blue Edible Electrochemical Transistors.一种基于溶液的沉积方法用于制备颜料蓝可食用电化学晶体管。

本文引用的文献

1
Device integration of electrochemical biosensors.电化学生物传感器的设备集成
Nat Rev Bioeng. 2023;1(5):346-360. doi: 10.1038/s44222-023-00032-w. Epub 2023 Feb 24.
2
Artificial neuron transmits chemical signals.人工神经元传递化学信号。
Nat Mater. 2023 Apr;22(4):416-418. doi: 10.1038/s41563-023-01509-0.
3
Point-of-care (POC) SARS-CoV-2 antigen detection using functionalized aerosol jet-printed organic electrochemical transistors (OECTs).使用功能化气溶胶喷射印刷有机电化学晶体管（OECTs）进行即时护理（POC）SARS-CoV-2抗原检测。
Adv Sci (Weinh). 2025 Aug;12(29):e2416141. doi: 10.1002/advs.202416141. Epub 2025 Feb 27.
4
A Conformationally Driven Mechanism in n-Type Doping of Naphthalene Diimide-Bithiophene Copolymer by 1H-Benzimidazoles.1H-苯并咪唑对萘二亚胺-联噻吩共聚物进行n型掺杂的构象驱动机制
Adv Sci (Weinh). 2025 Apr;12(15):e2402482. doi: 10.1002/advs.202402482. Epub 2025 Feb 20.
5
Mixed Ionic and Electronic Conductivity in a Tetrathiafulvalene-Phosphonate Metal-Organic Framework.四硫富瓦烯膦酸金属有机框架中的混合离子与电子传导性
J Am Chem Soc. 2025 Jan 8;147(1):63-68. doi: 10.1021/jacs.4c13792. Epub 2024 Dec 19.
6
A Study of the Drift Phenomena of Gate-Functionalized Biosensors and Dual-Gate-Functionalized Biosensors in Human Serum.门控功能化生物传感器和双门控功能化生物传感器在人血清中的漂移现象研究。
Molecules. 2024 Mar 25;29(7):1459. doi: 10.3390/molecules29071459.
Nanoscale. 2023 Mar 16;15(11):5476-5485. doi: 10.1039/d2nr06485e.
4
Vertical organic electrochemical transistors for complementary circuits.垂直型有机电化学晶体管用于互补电路。
Nature. 2023 Jan;613(7944):496-502. doi: 10.1038/s41586-022-05592-2. Epub 2023 Jan 18.
5
A guide for the characterization of organic electrochemical transistors and channel materials.有机电化学晶体管及沟道材料特性表征指南。
Chem Soc Rev. 2023 Feb 6;52(3):1001-1023. doi: 10.1039/d2cs00920j.
6
Ion-tunable antiambipolarity in mixed ion-electron conducting polymers enables biorealistic organic electrochemical neurons.离子可调反双极性在混合离子-电子导电聚合物中实现了生物逼真的有机电化学神经元。
Nat Mater. 2023 Feb;22(2):242-248. doi: 10.1038/s41563-022-01450-8. Epub 2023 Jan 12.
7
Biological modulating organic photoelectrochemical transistor through in situ enzymatic engineering of photoactive gate for sensitive detection of serum alkaline phosphatase.通过对光活性栅极的原位酶工程化来生物调节有机光电晶体管，用于灵敏检测血清碱性磷酸酶。
Biosens Bioelectron. 2022 Dec 15;218:114752. doi: 10.1016/j.bios.2022.114752. Epub 2022 Sep 27.
8
Switching p-type to high-performance n-type organic electrochemical transistors via doped state engineering.通过掺杂态工程将p型转换为高性能n型有机电化学晶体管。
Nat Commun. 2022 Oct 10;13(1):5970. doi: 10.1038/s41467-022-33553-w.
9
Organic Mixed Ion-Electron Conductivity in Polymer Hybrid Systems.聚合物杂化体系中的有机混合离子-电子导电性
ACS Omega. 2022 Sep 8;7(37):32849-32862. doi: 10.1021/acsomega.2c04516. eCollection 2022 Sep 20.
10
Sensitive organic electrochemical transistor biosensors: Comparing single and dual gate functionalization and different COOH-functionalized bioreceptor layers.敏感型有机电化学晶体管生物传感器：比较单栅和双栅功能化以及不同的 COOH 功能化生物受体层。
Biosens Bioelectron. 2022 Nov 15;216:114691. doi: 10.1016/j.bios.2022.114691. Epub 2022 Sep 6.