• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

围绝经期综合征的诊断与治疗进展

Advances in diagnosis and treatment of perimenopausal syndrome.

作者信息

Chen Wanying, Chen Mengjuan, Tang Huimin, Wei Weiwei, Shao Panqiu, Dou Shulan, Wu Jia, Lu Bingying, Shi Ruxia, Chen Jiming

机构信息

Department of Gynecology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, Jiangsu, 213003, PR China.

Zhoukou Maternal and Child Health Hospital, Zhoukou, Henan, 466000, PR China.

出版信息

Open Life Sci. 2023 Dec 22;18(1):20220754. doi: 10.1515/biol-2022-0754. eCollection 2023.

DOI:10.1515/biol-2022-0754
PMID:38152579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10751995/
Abstract

With the development and progress of society, people's average life expectancy has increased, and relevant literature reports that the number of postmenopausal women in China continues to increase. With lifespans extended, the transition period and post-menopause period have become the longest essential period in every woman's life. The life quality of women troubled by perimenopausal syndrome has been significantly reduced, which also places a burden on families and society. It is well known that hormone replacement therapy plays a vital role in improving women's menopause-related symptoms and is the most effective medical measure. With research ongoing into the treatment of menopausal symptoms in different patients, dose size, treatment duration, and medication regimens for hormones are still hot topics of discussion. This article reviews the definition, clinical diagnosis, staging, clinical manifestations, and treatment of menopause and explores the current diagnosis and treatment scenarios of perimenopausal syndrome.

摘要

随着社会的发展与进步,人们的平均预期寿命有所提高,相关文献报道中国绝经后女性的数量持续增加。随着寿命的延长,围绝经期和绝经后期已成为每位女性生命中最长的关键时期。受围绝经期综合征困扰的女性生活质量显著下降,这也给家庭和社会带来了负担。众所周知,激素替代疗法在改善女性绝经相关症状方面发挥着至关重要的作用,是最有效的医学措施。随着针对不同患者绝经症状治疗的研究不断深入,激素的剂量大小、治疗时长和用药方案仍是热门讨论话题。本文综述了绝经的定义、临床诊断、分期、临床表现及治疗,并探讨了围绝经期综合征的当前诊断和治疗情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a9e/10751995/39ac94ca3fac/j_biol-2022-0754-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a9e/10751995/e289bbf3689f/j_biol-2022-0754-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a9e/10751995/eb188f6ede21/j_biol-2022-0754-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a9e/10751995/c08193f9a5f9/j_biol-2022-0754-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a9e/10751995/39ac94ca3fac/j_biol-2022-0754-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a9e/10751995/e289bbf3689f/j_biol-2022-0754-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a9e/10751995/eb188f6ede21/j_biol-2022-0754-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a9e/10751995/c08193f9a5f9/j_biol-2022-0754-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a9e/10751995/39ac94ca3fac/j_biol-2022-0754-fig004.jpg

相似文献

1
Advances in diagnosis and treatment of perimenopausal syndrome.围绝经期综合征的诊断与治疗进展
Open Life Sci. 2023 Dec 22;18(1):20220754. doi: 10.1515/biol-2022-0754. eCollection 2023.
2
The Impact of Soy Isoflavone Supplementation on the Menopausal Symptoms in Perimenopausal and Postmenopausal Women.补充大豆异黄酮对围绝经期和绝经后妇女绝经症状的影响。
J Midlife Health. 2022 Apr-Jun;13(2):175-184. doi: 10.4103/jmh.jmh_190_21. Epub 2022 Sep 16.
3
Clinical challenges of perimenopause: consensus opinion of The North American Menopause Society.围绝经期的临床挑战:北美更年期协会的共识意见
Menopause. 2000 Jan-Feb;7(1):5-13.
4
Black cohosh (Cimicifuga spp.) for menopausal symptoms.黑升麻(升麻属植物)用于缓解更年期症状。
Cochrane Database Syst Rev. 2012 Sep 12;2012(9):CD007244. doi: 10.1002/14651858.CD007244.pub2.
5
Population-based survey on menopausal symptoms and treatment use.基于人群的绝经症状及治疗使用情况调查。
Climacteric. 2023 Feb;26(1):47-54. doi: 10.1080/13697137.2022.2139598. Epub 2022 Nov 9.
6
Prognostic features of menopausal and postmenopausal applicants for life insurance.更年期及绝经后寿险申请人的预后特征。
J Insur Med. 1996;28(1):27-34.
7
The effects of compounded bioidentical transdermal hormone therapy on hemostatic, inflammatory, immune factors; cardiovascular biomarkers; quality-of-life measures; and health outcomes in perimenopausal and postmenopausal women.复合生物等效透皮激素疗法对围绝经期和绝经后女性的止血、炎症、免疫因子、心血管生物标志物、生活质量指标及健康结局的影响。
Int J Pharm Compd. 2013 Jan-Feb;17(1):74-85.
8
Depression or menopause? Presentation and management of major depressive disorder in perimenopausal and postmenopausal women.抑郁症还是更年期?围绝经期和绝经后女性重度抑郁症的表现与管理
Prim Care Companion J Clin Psychiatry. 2010;12(1):PCC.08r00747. doi: 10.4088/PCC.08r00747blu.
9
Menopausal Symptoms and Perimenopausal Healthcare-Seeking Behavior in Women Aged 40-60 Years: A Community-Based Cross-Sectional Survey in Shanghai, China.40-60 岁女性绝经期症状与围绝经期保健求医行为:中国上海社区横断面调查。
Int J Environ Res Public Health. 2020 Apr 12;17(8):2640. doi: 10.3390/ijerph17082640.
10
The Effect of Soy Isoflavones on the Menopause Rating Scale Scoring in Perimenopausal and Postmenopausal Women: A Pilot Study.大豆异黄酮对围绝经期和绝经后女性更年期评定量表评分的影响:一项初步研究
J Clin Diagn Res. 2017 Sep;11(9):FC13-FC16. doi: 10.7860/JCDR/2017/26034.10654. Epub 2017 Sep 1.

引用本文的文献

1
Knowledge, Attitudes, and Practices Towards Hormone Replacement Therapy Among Women with Perimenopausal Syndrome: A Cross-Sectional Analysis in Quzhou, Zhejiang Province, China.围绝经期综合征女性对激素替代疗法的知识、态度和实践:中国浙江省衢州市的横断面分析
Int J Womens Health. 2025 Jul 22;17:2265-2276. doi: 10.2147/IJWH.S513067. eCollection 2025.
2
Investigation of the quality of life and influencing factors among perimenopausal women.围绝经期女性生活质量及其影响因素调查
Arch Gynecol Obstet. 2025 Jul 23. doi: 10.1007/s00404-025-08116-1.
3
Analysis of Menopausal Hormone Therapy to Chinese Patients with Menopausal Syndrome: A Real-World Retrospective Study from Chinese Hospitals.

本文引用的文献

1
World Health Organization 2020 guidelines on physical activity and sedentary behaviour.世界卫生组织 2020 年关于身体活动和 sedentary behaviour 的指南。
Br J Sports Med. 2020 Dec;54(24):1451-1462. doi: 10.1136/bjsports-2020-102955.
2
The 2020 genitourinary syndrome of menopause position statement of The North American Menopause Society.北美更年期协会2020年更年期泌尿生殖综合征立场声明
Menopause. 2020 Sep;27(9):976-992. doi: 10.1097/GME.0000000000001609.
3
A critical appraisal of vasomotor symptom assessment tools used in clinical trials evaluating hormone therapy compared to placebo.
中国绝经综合征患者的绝经激素治疗分析:一项来自中国医院的真实世界回顾性研究
Drug Des Devel Ther. 2025 Jun 4;19:4861-4873. doi: 10.2147/DDDT.S517420. eCollection 2025.
4
Social Support and Its Influencing Factors Among Perimenopausal Women in Tianjin, China: A Community-Based Study.中国天津围绝经期女性的社会支持及其影响因素:一项基于社区的研究
Healthcare (Basel). 2025 May 4;13(9):1057. doi: 10.3390/healthcare13091057.
5
Effectiveness and safety of hormone replacement therapy in the treatment of menopausal syndrome: a meta-analysis.激素替代疗法治疗更年期综合征的有效性和安全性:一项荟萃分析。
Am J Transl Res. 2025 Jan 15;17(1):1-15. doi: 10.62347/UGLT3830. eCollection 2025.
6
Health inequality and improvement gap in the prevalence of gynecological cancers among perimenopausal women globally, 1990-2019.1990 - 2019年全球围绝经期女性妇科癌症患病率的健康不平等与改善差距
BMC Public Health. 2025 Feb 12;25(1):590. doi: 10.1186/s12889-025-21807-3.
7
Clinical efficacy of gamma-oryzanol combined with Femoston for perimenopausal syndrome.γ-谷维素联合替勃龙治疗围绝经期综合征的临床疗效
World J Clin Cases. 2024 Aug 6;12(22):4992-4998. doi: 10.12998/wjcc.v12.i22.4992.
8
Integrating network pharmacology with experimental validation to investigate the mechanism of Wuwei Zishen formula in improving perimenopausal syndrome.整合网络药理学与实验验证以探究五味滋肾方改善围绝经期综合征的机制。
Am J Transl Res. 2024 Jun 15;16(6):2190-2211. doi: 10.62347/RQHY5963. eCollection 2024.
9
Association between gut microbiota and menstrual disorders: a two-sample Mendelian randomization study.肠道微生物群与月经紊乱之间的关联:一项两样本孟德尔随机化研究。
Front Microbiol. 2024 Mar 7;15:1321268. doi: 10.3389/fmicb.2024.1321268. eCollection 2024.
对用于评估激素治疗与安慰剂相比的临床试验中血管舒缩症状评估工具的严格评价。
Menopause. 2019 Nov;26(11):1334-1341. doi: 10.1097/GME.0000000000001387.
4
Pharmacotherapeutic approaches to treating depression during the perimenopause.绝经前期间治疗抑郁症的药物治疗方法。
Expert Opin Pharmacother. 2019 Oct;20(15):1837-1845. doi: 10.1080/14656566.2019.1645122. Epub 2019 Jul 29.
5
Making choices at menopause.绝经后的选择。
Aust J Gen Pract. 2019 Jul;48(7):457-462. doi: 10.31128/AJGP-02-19-4851.
6
Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.195 个国家 1990 年至 2017 年饮食风险对健康的影响:2017 年全球疾病负担研究的系统分析。
Lancet. 2019 May 11;393(10184):1958-1972. doi: 10.1016/S0140-6736(19)30041-8. Epub 2019 Apr 4.
7
Relation of Pregnancy Loss to Risk of Cardiovascular Disease in Parous Postmenopausal Women (From the Women's Health Initiative).妊娠丢失与经产绝经后妇女心血管疾病风险的关系(来自妇女健康倡议)。
Am J Cardiol. 2019 May 15;123(10):1620-1625. doi: 10.1016/j.amjcard.2019.02.012. Epub 2019 Feb 22.
8
Menopause Symptom Management in the United Kingdom.英国的更年期症状管理
Nurs Clin North Am. 2018 Jun;53(2):263-277. doi: 10.1016/j.cnur.2018.01.004. Epub 2018 Apr 7.
9
Efficacy of Transdermal Estradiol and Micronized Progesterone in the Prevention of Depressive Symptoms in the Menopause Transition: A Randomized Clinical Trial.经皮雌二醇和微粒化黄体酮预防更年期过渡性抑郁症状的疗效:一项随机临床试验。
JAMA Psychiatry. 2018 Feb 1;75(2):149-157. doi: 10.1001/jamapsychiatry.2017.3998.
10
The 2017 hormone therapy position statement of The North American Menopause Society.北美更年期协会2017年激素治疗立场声明。
Menopause. 2017 Jul;24(7):728-753. doi: 10.1097/GME.0000000000000921.