Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA.
Westat Inc, Rockville, MD, USA.
J Natl Cancer Inst. 2024 May 8;116(5):737-744. doi: 10.1093/jnci/djae001.
Industrial facilities are not located uniformly across communities in the United States, but how the burden of exposure to carcinogenic air emissions may vary across population characteristics is unclear. We evaluated differences in carcinogenic industrial pollution among major sociodemographic groups in the United States and Puerto Rico.
We evaluated cross-sectional associations of population characteristics including race and ethnicity, educational attainment, and poverty at the census tract level with point-source industrial emissions of 21 known human carcinogens using regulatory data from the US Environmental Protection Agency. Odds ratios and 95% confidence intervals comparing the highest emissions (tertile or quintile) to the referent group (zero emissions [ie, nonexposed]) for all sociodemographic characteristics were estimated using multinomial, population density-adjusted logistic regression models.
In 2018, approximately 7.4 million people lived in census tracts with nearly 12 million pounds of carcinogenic air releases. The odds of tracts having the greatest burden of benzene, 1,3-butadiene, ethylene oxide, formaldehyde, trichloroethylene, and nickel emissions compared with nonexposed were 10%-20% higher for African American populations, whereas White populations were up to 18% less likely to live in tracts with the highest emissions. Among Hispanic and Latino populations, odds were 16%-21% higher for benzene, 1,3-butadiene, and ethylene oxide. Populations experiencing poverty or with less than high school education were associated with up to 51% higher burden, irrespective of race and ethnicity.
Carcinogenic industrial emissions disproportionately impact African American and Hispanic and Latino populations and people with limited education or experiencing poverty thus representing a source of pollution that may contribute to observed cancer disparities.
在美国,工业设施并非均匀分布在各个社区,但是人们暴露于致癌空气排放物的负担如何因人口特征而异尚不清楚。我们评估了美国和波多黎各主要社会人口群体之间致癌工业污染的差异。
我们使用美国环境保护署的监管数据,评估了人口特征(包括种族和民族、教育程度和贫困程度)与点源工业排放 21 种已知人类致癌物之间的横断面关联。使用多变量、人口密度调整的逻辑回归模型,估算了所有社会人口特征的最高排放(三分位数或五分位数)与参照组(零排放[即未暴露])之间的比值比和 95%置信区间。
2018 年,约有 740 万人生活在致癌空气释放量近 1200 万磅的普查区。与未暴露相比,非裔美国人居住在苯、1,3-丁二烯、环氧乙烷、甲醛、三氯乙烯和镍排放负担最大的普查区的几率高 10%-20%,而白人居住在排放最高普查区的几率低 18%。在西班牙裔和拉丁裔人群中,苯、1,3-丁二烯和环氧乙烷的几率高 16%-21%。贫困或受教育程度低于高中的人群的负担增加了 51%,无论其种族和民族如何。
致癌工业排放不成比例地影响非裔美国人和西班牙裔和拉丁裔人群以及受教育程度低或贫困的人群,这代表了一种可能导致观察到的癌症差异的污染来源。