Sanya Institute, Hainan Academy of Agricultural Sciences (Hainan Experimental Animal Research Center), Sanya, 572000, Hainan, China.
Institute of Animal Husbandry and Veterinary Medicine, Hainan Key Laboratory for Tropical Animal Breeding and Disease Research, Hainan Academy of Agricultural Sciences, Haikou, 571100, Hainan, China.
BMC Vet Res. 2024 Jan 6;20(1):13. doi: 10.1186/s12917-023-03859-y.
Microbial fermented feed (MF) is considered a valuable strategy to bring advantages to livestock and is widely practiced. Oral supplementation of Ginseng polysaccharide (Gps) eliminated weight loss in chickens following vaccination. This study investigated the effects of the combined use of Gps and MF on growth performance and immune indices in Xuefeng black-bone chickens. A total of 400 Xuefeng black-bone chickens at the age of 1 day were randomly assigned to four groups. Normal feed group (Control group), ginseng polysaccharide (200 mg/kg) group (Gps group), microbially fermented feed (completely replace the normal feed) group (MF group), and microbially fermented feed and add ginseng polysaccharide just before use (MF + Gps group). Each group contained 5 pens per treatment and 20 birds per pen. The body weight and average daily gain in the Gps, MF, and MF + Gps groups increased significantly (P < 0.01), while the feed conversion ratio decreased significantly (P < 0.01). The combined use of MF and Gps showed a synergistic effect. There was no significant difference in villus height (cecal) between the experimental group and the Con group. The crypt depth of the three experimental groups exhibited a significantly lower value compared to the Control group (P < 0.05). The V/C ratio of the Gps group and MF + Gps was significantly increased (P < 0.05), but there was no significant difference in the MF group. Moreover, the diarrhea rate of the Gps and the MF + Gps groups was lower than that of the Con group, while that of the MF + Gps group decreased the mortality rate (P < 0.05). The serum tumor necrosis factor-alpha (TNF-α) and interleukin 6 (IL-6) levels in the MF, Gps, and MF + Gps groups decreased significantly (P < 0.01), the serum immunoglobulin G (IgG) levels increased significantly (P < 0.01), while the combination of MF and Gps had a synergistic effect. The combined use of Gps and MF not only further improved growth performance and immune parameters, but also reduced the diarrhea rate and mortality.
微生物发酵饲料（MF）被认为是一种为家畜带来优势的有价值策略，因此被广泛应用。口服人参多糖（Gps）可消除鸡在接种后的体重减轻。本研究旨在探讨人参多糖（Gps）和 MF 联合使用对雪峰黑骨鸡生长性能和免疫指标的影响。共选择 1 日龄的雪峰黑骨鸡 400 只，随机分为 4 组。正常饲料组（对照组）、人参多糖（200mg/kg）组（Gps 组）、微生物发酵饲料组（完全替代正常饲料）（MF 组）、微生物发酵饲料加用前添加人参多糖组（MF+Gps 组）。每组 5 个重复，每个重复 20 只鸡。Gps、MF 和 MF+Gps 组的体重和平均日增重显著增加（P<0.01），饲料转化率显著降低（P<0.01）。MF 和 Gps 联合使用具有协同作用。实验组与对照组的盲肠绒毛高度无显著差异。三个实验组的隐窝深度与对照组相比显著降低（P<0.05）。Gps 组和 MF+Gps 组的 V/C 比值显著增加（P<0.05），但 MF 组无显著差异。此外，Gps 组和 MF+Gps 组的腹泻率低于对照组，而 MF+Gps 组的死亡率降低（P<0.05）。MF、Gps 和 MF+Gps 组的血清肿瘤坏死因子-α（TNF-α）和白细胞介素 6（IL-6）水平显著降低（P<0.01），血清免疫球蛋白 G（IgG）水平显著升高（P<0.01），MF 和 Gps 联合使用具有协同作用。Gps 和 MF 的联合使用不仅进一步提高了生长性能和免疫参数，还降低了腹泻率和死亡率。
