Zhang Hongyue, Xie Jiaxin, Lu Bo, Chen Yichen, Ding Yibo, Zhang Yue, Xu Shuogui, Li Xiaopan
Department of Orthopedics, First Affiliated Hospital of Naval Medical University Shanghai 200433, China.
Department of High-Altitude Operational Medicine, Army Medical University Chongqing 400038, China.
Am J Transl Res. 2023 Dec 15;15(12):6832-6840. eCollection 2023.
The long-term trends in crude mortality rates (CMRs) and age-standardized mortality rates characterized by Segi's world standard population (ASMRWs) of DMSCT in Pudong New Area (PNA), Shanghai, were evaluated from 1973 to 2019, and the role of demographic and non-demographic factors in the mortality of diseases of the musculoskeletal system and connective tissue (DMSCT) was explored.
The PNA district has the largest population and area in Shanghai. Therefore, the mortality registration system of the PNA district was used to calculate and verify the number of deaths. Then, the Joinpoint Regression Program was used to analyze the time trend of mortality. The difference decomposition method was used to visualize the mortality of population and non-population factors, and GraphPad Prism was used for image visualization.
A total of 2260 deaths from DMSCT occurred from 1973 to 2019. The CMR and ASMRW of DMSCT were 2.56/105 person-years and 1.57/105 person-years, respectively. The number of people aged ≥80 (696 deaths) who died of DMSCT was the highest among total deaths, the highest number of years of life lost (YLL) was observed in the 45-59 age group, and the YLL rate in the ≥80 age group was the highest. The CMR and YLL rates of DMSCT showed upward trends in the total population from 1973 to 2019.
The CMR and YLL rates of DMSCT showed upward trends in the total population from 1973 to 2019 in PNA, Shanghai, and age was closely related to the occurrence of DMSCT. Similarly, demographic factors played a role in this process.
评估1973年至2019年上海浦东新区（PNA）肌肉骨骼系统和结缔组织疾病（DMSCT）的粗死亡率（CMR）和以Segi世界标准人口为特征的年龄标准化死亡率（ASMRW）的长期趋势，并探讨人口和非人口因素在DMSCT死亡率中的作用。
浦东新区是上海人口最多、面积最大的区。因此，利用浦东新区的死亡登记系统计算并核实死亡人数。然后，使用Joinpoint回归程序分析死亡率的时间趋势。采用差异分解法直观呈现人口和非人口因素的死亡率，并使用GraphPad Prism进行图像可视化。
1973年至2019年共发生2260例DMSCT死亡。DMSCT的CMR和ASMRW分别为2.56/10万人年和1.57/10万人年。死于DMSCT的≥80岁人群（696例死亡）在总死亡人数中最多，45-59岁年龄组的生命损失年数（YLL）最高，≥80岁年龄组的YLL率最高。1973年至2019年，DMSCT的CMR和YLL率在总人口中呈上升趋势。
1973年至2019年，上海浦东新区DMSCT的CMR和YLL率在总人口中呈上升趋势，年龄与DMSCT的发生密切相关。同样，人口因素在这一过程中发挥了作用。
