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基于金纳米颗粒的比色生物传感用于食源性病原体检测。

Gold Nanoparticle-Based Colorimetric Biosensing for Foodborne Pathogen Detection.

作者信息

Park Sang-Hyun, You Youngsang

机构信息

Department of Food Science and Technology, Kongju National University, Yesan 32439, Chungnam, Republic of Korea.

Department of Food Engineering, Dankook University, Cheonan 31116, Chungnam, Republic of Korea.

出版信息

Foods. 2023 Dec 27;13(1):95. doi: 10.3390/foods13010095.

DOI:10.3390/foods13010095
PMID:38201122
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10778349/
Abstract

Ensuring safe high-quality food is an ongoing priority, yet consumers face heightened risk from foodborne pathogens due to extended supply chains and climate change in the food industry. Nanomaterial-based assays are popular and have recently been developed to ensure food safety and high quality. This review discusses strategies for utilizing gold nanoparticles in colorimetric biosensors. The visible-signal biosensor proves to be a potent sensing technique for directly measuring targets related to foodborne pathogens in the field of food analysis. Among visible-signal biosensors, the localized surface plasmon resonance (LSPR) biosensor has garnered increasing attention and experienced rapid development in recent years. This review succinctly introduces the origin of LSPR theory, providing detailed insights into its fundamental principles. Additionally, this review delves into the application of nanotechnology for the implementation of the LSPR biosensor, exploring methods for utilizing gold nanoparticles and elucidating the factors that influence the generation of visible signals. Several emerging technologies aimed at simple and rapid immunoassays for onsite applications have been introduced in the food industry. In the foreseeable future, field-friendly colorimetric biosensors could be adopted in food monitoring systems. The onsite and real-time detection of possible contaminants and biological substances in food and water is essential to ensure human health and safety.

摘要

确保安全的高质量食品是一项持续的优先事项,然而,由于食品行业供应链的延长和气候变化,消费者面临食源性病原体带来的更高风险。基于纳米材料的检测方法很受欢迎,并且最近已被开发用于确保食品安全和高质量。本综述讨论了在比色生物传感器中利用金纳米颗粒的策略。可见信号生物传感器被证明是一种强大的传感技术,可直接测量食品分析领域中与食源性病原体相关的目标。在可见信号生物传感器中,局域表面等离子体共振(LSPR)生物传感器近年来受到越来越多的关注并经历了快速发展。本综述简要介绍了LSPR理论的起源,详细阐述了其基本原理。此外,本综述深入探讨了纳米技术在LSPR生物传感器中的应用,探索了利用金纳米颗粒的方法,并阐明了影响可见信号产生的因素。食品行业已经引入了几种旨在实现现场应用的简单快速免疫分析的新兴技术。在可预见的未来,现场友好型比色生物传感器可能会被应用于食品监测系统。对食品和水中可能的污染物和生物物质进行现场实时检测对于确保人类健康和安全至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef23/10778349/8708f40fe6ca/foods-13-00095-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef23/10778349/ecba26e6889e/foods-13-00095-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef23/10778349/22fa9f38a478/foods-13-00095-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef23/10778349/3c53506d274c/foods-13-00095-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef23/10778349/8708f40fe6ca/foods-13-00095-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef23/10778349/ecba26e6889e/foods-13-00095-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef23/10778349/22fa9f38a478/foods-13-00095-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef23/10778349/3c53506d274c/foods-13-00095-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef23/10778349/8708f40fe6ca/foods-13-00095-g004.jpg

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