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及其作用机制的生物活性与纳米颗粒合成——综述

Biological Activities and Nanoparticle Synthesis of and its Mechanistic Action - An Extensive Review.

作者信息

Yadav Sangilimuthu Alagar, Hasan Shiek, Gnanaselvan Suvathika, Baskaran Santhoshraman, Danaraj Jayapragash

机构信息

Department of Biotechnology, Karpagam Academy of Higher Education, Coimbatore, 641 021, Tamil Nadu, India.

Centre for Ocean Research, Sathyabama Research Park, Sathyabama Institute of Science and Technology, Chennai, 600 119, India.

出版信息

Pharm Nanotechnol. 2024;12(5):379-390. doi: 10.2174/0122117385284106240110065809.

DOI:10.2174/0122117385284106240110065809
PMID:38265372
Abstract

BACKGROUND

is commonly known as air potato present in the tropical and subtropical regions. It is a perennial climber traditionally used for various therapeutic purposes by traditional healers. This review explores various medicinal uses of and its active ingredients, as well as describes its nanoparticle synthesis for medical applications.

METHODS

The Google Scholar search engine was used to conduct this comprehensive review along with the databases of the following publishers: Elsevier, Springer, Taylor and Francis, Bentham, and PubMed.

DISCUSSION

contains several bioactive compounds that are responsible for its pharmacological properties, such as antioxidant, anti-inflammatory, neuroprotective, anticancer, and antidiabetic properties. It is also used as a nutritive functional food. -mediated nanoparticle synthesis has been established by the scientific communities for various medicinal applications.

CONCLUSION

contains numerous active ingredients, including diosbulbins, bafoudiosbulbin, β-sitosterol, diosgenin, dioscin, pennogenin, myricetin, quercetin, and stigmasterols with numerous biological activities. In addition, it has a vital role in synthesizing nanoparticles with good pharmacological applications, especially in drug delivery systems. However, its potential characteristic features and functional properties of the active molecules present in this tuber need to be further explored in clinical trials. We suggest that using this edible tuber, we may formulate the valueadded food with good medicinal applications.

摘要

背景

通常被称为“空气土豆”,生长于热带和亚热带地区。它是一种多年生攀缘植物,传统上被传统治疗师用于各种治疗目的。本综述探讨了其各种药用用途及其活性成分,并描述了其用于医学应用的纳米颗粒合成。

方法

使用谷歌学术搜索引擎以及以下出版商的数据库进行了这项全面综述:爱思唯尔、施普林格、泰勒与弗朗西斯、边沁和PubMed。

讨论

含有多种生物活性化合物,这些化合物赋予了其药理特性,如抗氧化、抗炎、神经保护、抗癌和抗糖尿病特性。它还被用作营养功能性食品。科学界已确立了其介导的纳米颗粒合成用于各种医学应用。

结论

含有多种活性成分,包括薯蓣素、巴福薯蓣素、β-谷甾醇、薯蓣皂苷元、薯蓣皂苷、原薯蓣皂苷元、杨梅素、槲皮素和豆甾醇,具有多种生物活性。此外,它在合成具有良好药理应用的纳米颗粒方面具有重要作用,尤其是在药物递送系统中。然而,其潜在的特征以及该块茎中存在的活性分子的功能特性需要在临床试验中进一步探索。我们建议,使用这种可食用块茎,我们可以配制出具有良好药用应用的增值食品。

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