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释放二硫化钨的潜力：生物传感与纳米医学应用的当前趋势。

Unleashing the potential of tungsten disulfide: Current trends in biosensing and nanomedicine applications.

作者信息

Bahri Mohamed, Yu Dongmei, Zhang Can Yang, Chen Zhenglin, Yang Chengming, Douadji Lyes, Qin Peiwu

机构信息

Center of Precision Medicine and Healthcare, Tsinghua-Berkeley Shenzhen Institute, Shenzhen, Guangdong Province, 518055, China.

Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.

出版信息

Heliyon. 2024 Jan 11;10(2):e24427. doi: 10.1016/j.heliyon.2024.e24427. eCollection 2024 Jan 30.

DOI:10.1016/j.heliyon.2024.e24427
PMID:38293340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10826743/
Abstract

The discovery of graphene ignites a great deal of interest in the research and advancement of two-dimensional (2D) layered materials. Within it, semiconducting transition metal dichalcogenides (TMDCs) are highly regarded due to their exceptional electrical and optoelectronic properties. Tungsten disulfide (WS) is a TMDC with intriguing properties, such as biocompatibility, tunable bandgap, and outstanding photoelectric characteristics. These features make it a potential candidate for chemical sensing, biosensing, and tumor therapy. Despite the numerous reviews on the synthesis and application of TMDCs in the biomedical field, no comprehensive study still summarizes and unifies the research trends of WS from synthesis to biomedical applications. Therefore, this review aims to present a complete and thorough analysis of the current research trends in WS across several biomedical domains, including biosensing and nanomedicine, covering antibacterial applications, tissue engineering, drug delivery, and anticancer treatments. Finally, this review also discusses the potential opportunities and obstacles associated with WS to deliver a new outlook for advancing its progress in biomedical research.

摘要

石墨烯的发现激发了人们对二维（2D）层状材料研究和发展的浓厚兴趣。其中，半导体过渡金属二硫属化物（TMDCs）因其卓越的电学和光电特性而备受关注。二硫化钨（WS）是一种具有有趣特性的TMDC，如生物相容性、可调节带隙和出色的光电特性。这些特性使其成为化学传感、生物传感和肿瘤治疗的潜在候选材料。尽管已有众多关于TMDCs在生物医学领域的合成与应用的综述，但仍没有全面的研究总结并统一WS从合成到生物医学应用的研究趋势。因此，本综述旨在对WS在多个生物医学领域（包括生物传感和纳米医学）的当前研究趋势进行完整而深入的分析，涵盖抗菌应用、组织工程、药物递送和抗癌治疗。最后，本综述还讨论了与WS相关的潜在机遇和障碍，为推动其在生物医学研究中的进展提供新的视角。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6265/10826743/598c12b5efc5/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6265/10826743/c8f6dbd260c2/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6265/10826743/60633af8aa55/gr14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6265/10826743/c0852cf35e52/gr15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6265/10826743/95d6001e0ed4/gr16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6265/10826743/433b08b7c460/gr17.jpg
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