Zhang Chunhong, Zhang Chenxi, Liu Yongchun
Xi'an Key Laboratory of Advanced Control and Intelligent Process, School of Automation, Xi'an University of Posts & Telecommunications, Xi'an 710121, China.
Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710119, China.
Nanomaterials (Basel). 2025 Feb 27;15(5):367. doi: 10.3390/nano15050367.
Flexible devices are soft, lightweight, and portable, making them suitable for large-area applications. These features significantly expand the scope of electronic devices and demonstrate their unique value in various fields, including smart wearable devices, medical and health monitoring, human-computer interaction, and brain-computer interfaces. Protein materials, due to their unique molecular structure, biological properties, sustainability, self-assembly ability, and good biocompatibility, can be applied in electronic devices to significantly enhance the sensitivity, stability, mechanical strength, energy density, and conductivity of the devices. Protein-based flexible devices have become an important research direction in the fields of bioelectronics and smart wearables, providing new material support for the development of more environmentally friendly and reliable flexible electronics. Currently, many proteins, such as silk fibroin, collagen, ferritin, and so on, have been used in biosensors, memristors, energy storage devices, and power generation devices. Therefore, in this paper, we provide an overview of related research in the field of protein-based flexible devices, including the concept and characteristics of protein-based flexible devices, fabrication materials, fabrication processes, characterization, and evaluation, and we point out the future development direction of protein-based flexible devices.
柔性器件柔软、轻便且便于携带，使其适用于大面积应用。这些特性显著扩展了电子器件的范围，并在包括智能可穿戴设备、医疗健康监测、人机交互和脑机接口等各个领域展现出其独特价值。蛋白质材料因其独特的分子结构、生物学特性、可持续性、自组装能力和良好的生物相容性，可应用于电子器件中，从而显著提高器件的灵敏度、稳定性、机械强度、能量密度和导电性。基于蛋白质的柔性器件已成为生物电子学和智能可穿戴领域的一个重要研究方向，为开发更环保、更可靠的柔性电子产品提供了新的材料支持。目前，许多蛋白质，如丝素蛋白、胶原蛋白、铁蛋白等，已被用于生物传感器、忆阻器、储能器件和发电器件中。因此，在本文中，我们对基于蛋白质的柔性器件领域的相关研究进行了综述，包括基于蛋白质的柔性器件的概念和特性、制造材料、制造工艺、表征和评估，并指出了基于蛋白质的柔性器件的未来发展方向。
