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人工智能在细菌感染识别与管理中的临床应用:系统评价与荟萃分析

Clinical applications of artificial intelligence in identification and management of bacterial infection: Systematic review and meta-analysis.

作者信息

Zubair Mohammad

机构信息

Department of Medical Microbiology, Faculty of Medicine, University of Tabuk, Tabuk 71491, Kingdom of Saudi Arabia.

出版信息

Saudi J Biol Sci. 2024 Mar;31(3):103934. doi: 10.1016/j.sjbs.2024.103934. Epub 2024 Jan 14.

DOI:10.1016/j.sjbs.2024.103934
PMID:38304541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10831261/
Abstract

Pneumonia is declared a global emergency public health crisis in children less than five age and the geriatric population. Recent advancements in deep learning models could be utilized effectively for the timely and early diagnosis of pneumonia in immune-compromised patients to avoid complications. This systematic review and -analysis utilized PRISMA guidelines for the selection of ten articles included in this study. The literature search was done through electronic databases including PubMed, Scopus, and Google Scholar from 1st January 2016 till 1 July 2023. Overall studies included a total of 126,610 images and 1706 patients in this -analysis. At a 95% confidence interval, for pooled sensitivity was 0.90 (0.85-0.94) and I2 statistics 90.20 (88.56 - 91.92). The pooled specificity for deep learning models' diagnostic accuracy was 0.89 (0.86---0.92) and I2 statistics 92.72 (91.50 - 94.83). I2 statistics showed low heterogeneity across studies highlighting consistent and reliable estimates, and instilling confidence in these findings for researchers and healthcare practitioners. The study highlighted the recent deep learning models single or in combination with high accuracy, sensitivity, and specificity to ensure reliable use for bacterial pneumonia identification and differentiate from other viral, fungal pneumonia in children and adults through chest x-rays and radiographs.

摘要

肺炎被宣布为五岁以下儿童和老年人群体中的全球紧急公共卫生危机。深度学习模型的最新进展可有效用于免疫功能低下患者肺炎的及时早期诊断,以避免并发症。本系统评价和分析采用PRISMA指南选择本研究纳入的十篇文章。文献检索通过电子数据库进行,包括PubMed、Scopus和谷歌学术,检索时间为2016年1月1日至2023年7月1日。在本次分析中,总体研究共纳入126,610张图像和1706名患者。在95%置信区间下,合并敏感度为0.90(0.85 - 0.94),I2统计量为90.20(88.56 - 91.92)。深度学习模型诊断准确性的合并特异度为0.89(0.86 - 0.92),I2统计量为92.72(91.50 - 94.83)。I2统计量显示各研究间异质性较低,突出了一致且可靠的估计,并增强了研究人员和医疗从业者对这些结果的信心。该研究强调了近期的深度学习模型单独或联合使用时具有高准确性、敏感度和特异度,可通过胸部X光和射线照片确保可靠用于儿童和成人细菌性肺炎的识别,并与其他病毒性、真菌性肺炎相鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a35/10831261/bba358340b8e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a35/10831261/d0ebadf77413/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a35/10831261/521578ddffdf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a35/10831261/bba358340b8e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a35/10831261/d0ebadf77413/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a35/10831261/521578ddffdf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a35/10831261/bba358340b8e/gr3.jpg

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本文引用的文献

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Eur J Radiol Open. 2022;9:100438. doi: 10.1016/j.ejro.2022.100438. Epub 2022 Aug 18.
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AI Based Diagnosis of Pneumonia.基于人工智能的肺炎诊断
Wirel Pers Commun. 2022;126(4):3677-3692. doi: 10.1007/s11277-022-09885-7. Epub 2022 Jun 29.
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Automatic detection of pneumonia in chest X-ray images using textural features.利用纹理特征自动检测胸部 X 光图像中的肺炎。
Comput Biol Med. 2022 Jun;145:105466. doi: 10.1016/j.compbiomed.2022.105466. Epub 2022 Mar 30.
4
Derivation and validation of a novel risk assessment tool to identify children aged 2-59 months at risk of hospitalised pneumonia-related mortality in 20 countries.一种新型风险评估工具的推导和验证,用于识别 20 个国家中 2-59 个月龄儿童因肺炎住院相关死亡风险的工具。
BMJ Glob Health. 2022 Apr;7(4). doi: 10.1136/bmjgh-2021-008143.
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Strengths and caveats of identifying resistance genes from whole genome sequencing data.从全基因组测序数据中识别抗性基因的优势和局限性。
Expert Rev Anti Infect Ther. 2022 Apr;20(4):533-547. doi: 10.1080/14787210.2022.2013806. Epub 2021 Dec 16.
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Pneumonia detection in chest X-ray images using an ensemble of deep learning models.使用深度学习模型集成进行胸部 X 射线图像中的肺炎检测。
PLoS One. 2021 Sep 7;16(9):e0256630. doi: 10.1371/journal.pone.0256630. eCollection 2021.
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