Hourizadeh Jason, Munshi Rezwan, Zeltser Roman, Makaryus Amgad N
Department of Internal Medicine, St. John's Riverside Hospital, Yonkers, NY, USA.
Department of Cardiology, Nassau University Medical Center, East Meadow, NY, USA.
Curr Cardiol Rev. 2024;20(2):82-92. doi: 10.2174/011573403X257173231222042846.
Dietary habits, such as the Mediterranean diet and the Dietary Approaches to Stop Hypertension (DASH), have been shown to improve cardiac health. Another more recent popular form of dieting incorporates periods of fasting known as intermittent fasting. The two main forms are alternate-day fasting and time-restricted eating.
PubMed search and literature review was undertaken. This review evaluates the current literature regarding the effects of the fasting dietary model and other types of fasting upon the lipid panel.
There have been studies that have shown that intermittent fasting does provide a benefit in cardiovascular health, weight loss, and hypertension. However, the effect on cholesterol and triglyceride levels during intermittent fasting is in question.
The effect that fasting has on one's lipid panel is unclear, there are studies that show that different forms of fasting affect the lipid panel in various ways. There are studies that show that intermittent fasting does improve one's lipid profile and provides health benefits. Randomized controlled clinical trials with a large sample size are needed to evaluate the effects that intermittent fasting has based on race, ethnicity, gender, obesity, dyslipidemia, diabetic and healthy patients, and will lead to definitive evidence of lipid panel outcomes beyond current evidence based solely upon observational cohorts with numerous and multifactorial confounding factors and biases.
饮食习惯，如地中海饮食和终止高血压膳食疗法（DASH），已被证明可改善心脏健康。另一种最近流行的节食方式包括被称为间歇性禁食的禁食期。两种主要形式是隔日禁食和限时进食。
进行了PubMed检索和文献综述。本综述评估了关于禁食饮食模式及其他类型禁食对血脂指标影响的当前文献。
有研究表明间歇性禁食确实对心血管健康、体重减轻和高血压有益。然而，间歇性禁食期间对胆固醇和甘油三酯水平的影响存在疑问。
禁食对一个人的血脂指标的影响尚不清楚，有研究表明不同形式的禁食以各种方式影响血脂指标。有研究表明间歇性禁食确实能改善一个人的血脂状况并带来健康益处。需要进行大样本量的随机对照临床试验，以评估基于种族、民族、性别、肥胖、血脂异常、糖尿病患者和健康患者的间歇性禁食的影响，这将得出超出目前仅基于存在众多和多因素混杂因素及偏差的观察性队列研究证据的血脂指标结果的确切证据。
