Meißner Anna-Katharina, Goldbrunner Roland, Neuschmelting Volker
Klinik für allgemeine Neurochirurgie, Zentrum für Neurochirurgie, Medizinische Fakultät und Universitätsklinik Köln, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Chirurgie (Heidelb). 2024 Apr;95(4):274-279. doi: 10.1007/s00104-024-02038-5. Epub 2024 Feb 9.
In brain tumor surgery a personalized surgical approach is crucial to achieve a maximum safe tumor resection. The extent of resection decisively depends on the histological diagnosis. Stimulated Raman histology (SRH), a fiber laser-based optical imaging method, offers the possibility for evaluation of an intraoperative diagnosis in a few minutes.
To provide an overview on the applications of SRH in neurosurgery and transference of the technique to other surgical disciplines.
Description of the technique and review of the current literature on SRH.
The SRH technique was successfully used in multiple neuro-oncological tumor entities. Initial pilot projects showed the potential for analysis of extracranial tumors.
The use of SRH provides a near real-time diagnosis with high diagnostic accuracy and provides further developmental potential to improve personalized tumor surgery.
在脑肿瘤手术中，个性化的手术方法对于实现最大程度的安全肿瘤切除至关重要。切除范围决定性地取决于组织学诊断。受激拉曼组织学（SRH）是一种基于光纤激光的光学成像方法，能够在几分钟内对术中诊断进行评估。
概述SRH在神经外科手术中的应用以及该技术向其他外科领域的转移。
描述该技术并回顾有关SRH的当前文献。
SRH技术已成功应用于多种神经肿瘤实体。初步的试点项目显示了分析颅外肿瘤的潜力。
使用SRH可提供具有高诊断准确性的近实时诊断，并为改善个性化肿瘤手术提供进一步的发展潜力。
