Alanija Lekha, Chandran Selvaraj Raaja Sreepathy, Ramamurthy Shanmugapriya, Ulaganathan Arunmozhi, C Vikram
Periodontology, Sri Venkateswara Dental College and Hospital, The Tamil Nadu Dr. M.G.R. Medical University, Chennai, IND.
Cureus. 2024 Jan 12;16(1):e52190. doi: 10.7759/cureus.52190. eCollection 2024 Jan.
Antihypertensives such as amlodipine, which is a family of calcium channel blockers (CCBs), possess a limitation by causing gingival enlargement on long-term use. Gingival enlargement hinders the patient's oral hygiene maintenance and causes more plaque accumulation and inflammation. The severity of the condition is dependent on dose and duration. When untreated, this leads to functional and esthetic disabilities. This is a case report of amlodipine-induced gingival enlargement in a young, chronic periodontitis patient who was under 5 mg of amlodipine for six months. Upon diagnosis, the patient underwent periodontal surgery and supportive periodontal therapy, which significantly improved her periodontal health in a one-year follow-up period.
抗高血压药物,如氨氯地平,属于钙通道阻滞剂(CCB)家族,长期使用会导致牙龈增生,存在局限性。牙龈增生妨碍患者保持口腔卫生,导致更多牙菌斑积聚和炎症。病情的严重程度取决于剂量和用药时长。若不治疗,会导致功能和美观方面的障碍。这是一例年轻慢性牙周炎患者因服用氨氯地平导致牙龈增生的病例报告,该患者服用5毫克以下氨氯地平六个月。诊断后,患者接受了牙周手术和支持性牙周治疗,在一年的随访期内,其牙周健康状况有显著改善。